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经皮微创椎间孔腰椎椎体间融合联合单侧椎弓根螺钉固定治疗椎间盘源性下腰痛

[Surgical treatment of discogenic low back pain by minimally invasive transforaminal lumbar interbody fusion combined with unilateral pedicle screw fixation].

作者信息

Liang Bowei, Zhao Jinmin, Li Ningning, Hu Zhaohui, Sun Hongzhi

机构信息

Department of Spine Surgery, Fifth Affiliated Hospital of Guangxi Medical University/Liuzhou People's Hospital, Liuzhou Guangxi 545006, PR China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2012 Mar;26(3):272-6.

Abstract

OBJECTIVE

To investigate the effectiveness of surgical treatment for discogenic low back pain (DLBP) by minimally invasive transforaminal lumbar interbody fusion (TLIF) combined with unilateral pedicle screw fixation (UPSF).

METHODS

Between March 2006 and July 2009, 57 patients with single-level DLBP were treated by minimally invasive TLIF combined with UPSF, including 27 males and 30 females with an average age of 45.6 years (range, 38-61 years) and a disease duration of 3.8 years (range, 9 months to 11 years). The involved segments included L2, 3 in 2 cases, L3, 4 in 5 cases, L4, 5 in 29 cases, and L5, S1 in 21 cases. The operative time, incision length, intraoperative blood loss, postoperative drainage volume, hospitalization times, fusion rate, and complications were observed. The effectiveness were evaluated through Oswestry disability index (ODI) and visual analogue score (VAS), and the operative outcomes were compared in different groups classified according to various pressures of the contrast medium and sensitivities to disc block after inducing consistent pain.

RESULTS

The operation time, incision length, blood loss, postoperative drainage volume, and hospitalization times were (84.6 +/- 37.4) minutes, (3.4 +/- 0.6) cm, (132.5 +/- 23.2) mL, (58.7 +/- 21.4) mL, and (6.5 +/- 0.8) days, respectively. All patients were followed up 2 years and 2 months to 5 years and 4 months (mean, 3.2 years). At last follow-up, ODI and VAS scores were significantly improved when compared with preoperative scores (P < 0.05). The effectiveness according to ODI were excellent in 27 cases, good in 22 cases, fair in 6 cases, and poor in 2 cases, with an excellent and good rate of 86.0%. All patients acquired strong interbody fusion. At last follow-up according to ODI and VAS scores, better results were found in patients of low-pressure sensitive group and high-sensitive disc block group (P < 0.05).

CONCLUSION

Minimally invasive TLIF combined with UPSF is reliable for DLBP with minimal surgical trauma, less paravertebral tissue injury, and fewer complications, but the indications for operation must be strictly followed. Patients being sensitive to low-pressure or high-sensitive to disc block can achieve better surgical results.

摘要

目的

探讨微创经椎间孔腰椎椎体间融合术(TLIF)联合单侧椎弓根螺钉固定术(UPSF)治疗椎间盘源性下腰痛(DLBP)的有效性。

方法

2006年3月至2009年7月,57例单节段DLBP患者接受了微创TLIF联合UPSF治疗,其中男性27例,女性30例,平均年龄45.6岁(范围38 - 61岁),病程3.8年(范围9个月至11年)。受累节段包括L2、3共2例,L3、4共5例,L4、5共29例,L5、S1共21例。观察手术时间、切口长度、术中出血量、术后引流量、住院时间、融合率及并发症。通过Oswestry功能障碍指数(ODI)和视觉模拟评分(VAS)评估疗效,并在诱导一致疼痛后根据造影剂不同压力及椎间盘阻滞敏感性将患者分为不同组,比较不同组的手术效果。

结果

手术时间、切口长度、出血量、术后引流量及住院时间分别为(84.6±37.4)分钟、(3.4±0.6)厘米、(132.5±23.2)毫升、(58.7±21.4)毫升和(6.5±0.8)天。所有患者随访2年2个月至5年4个月(平均3.2年)。末次随访时,ODI和VAS评分与术前相比显著改善(P < 0.05)。根据ODI评估疗效,优27例,良22例,可6例,差2例,优良率为86.0%。所有患者均获得坚强的椎体间融合。末次随访时,根据ODI和VAS评分,低压敏感组和高敏感椎间盘阻滞组患者效果更佳(P < 0.05)。

结论

微创TLIF联合UPSF治疗DLBP可靠,手术创伤小,椎旁组织损伤少,并发症少,但必须严格遵循手术适应证。对低压敏感或对椎间盘阻滞高敏感的患者可获得更好的手术效果。

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