Gleave E N, Whittaker J S, Nicholson A
Clin Otolaryngol Allied Sci. 1979 Aug;4(4):247-57. doi: 10.1111/j.1365-2273.1979.tb01897.x.
A clinicopathological survey of tumours of salivary glands seen in a special surgical clinic at the Christie Hospital and Holt Radium Institute is reported. Nine hundred and seventy-seven benign and malignant tumours have been seen within the past 30 years. The results of treatment are included with particular attention to those of the parotid glands which present the greatest therapeutic problem. The approach to surgical treatment of pleomorphic adenomas is described in detail and guidelines offered as to the procedure that should be used based on full exploration and assessment of each tumour. The need for adjuvant irradiation depends on the standard of surgery that is done. The relationship between carcinomas and benign adenomas is discussed and the need for surgery in all cases is stressed in order to make a definite histological diagnosis in view of the wide range of pathological abnormality encountered.
本文报告了在克里斯蒂医院和霍尔特镭研究所的一家特殊外科诊所中对唾液腺肿瘤进行的临床病理调查。在过去30年里共诊治了977例良性和恶性肿瘤。文中包含了治疗结果,尤其关注了腮腺肿瘤,其带来了最大的治疗难题。详细描述了多形性腺瘤的手术治疗方法,并根据对每个肿瘤的全面探查和评估,给出了应采用的手术步骤指南。辅助放疗的必要性取决于所施行手术的水平。文中讨论了癌与良性腺瘤的关系,并强调在所有病例中都需要进行手术,以便鉴于所遇到的广泛病理异常做出明确的组织学诊断。