Thomas Jefferson University Hospital, Philadelphia, PA 19106, USA.
J Pediatr Urol. 2012 Oct;8(5):e55-8. doi: 10.1016/j.jpurol.2012.03.006. Epub 2012 Apr 14.
Metastatic Crohn's disease is a rare and complex inflammatory condition distinguished by cutaneous granulomatous lesions outside the gastrointestinal tract. Genital involvement is rare; with less than 10 cases reported involving isolated penile lymphedema. Here, we present a case of isolated lymphedema of the penis as a consequence of extra-intestinal Crohn's disease.
The patient is an 18-year-old African American male with a complex history of inflammatory bowel disease, who initially presented with a chief complaint of 6 weeks of swelling of his penis at age 13. A modified circumcision and lymphangectomy of the penis were performed; histopatholgy demonstrated a granulomatous infiltrate and interstitial edema of the distal penis.
Surgical intervention is an applicable therapeutic alternative and last-line therapy for treatment of isolated penile lymphedema in select patients with appropriate pathology, and can be a suitable adjunct to medical management in these cases.
转移性克罗恩病是一种罕见且复杂的炎症性疾病,其特征是胃肠道外出现皮肤肉芽肿性病变。生殖器受累较为罕见;报告的病例中,仅有不到 10 例涉及孤立性阴茎淋巴水肿。在此,我们报告了一例因肠道外克罗恩病导致的孤立性阴茎淋巴水肿病例。
患者为 18 岁非裔美国男性,具有复杂的炎症性肠病史,最初在 13 岁时主诉阴茎肿胀 6 周。进行了改良式阴茎环切术和淋巴管切除术;组织病理学显示远端阴茎有肉芽肿性浸润和间质水肿。
对于某些特定病理类型的患者,手术干预是一种可行的治疗选择,也是治疗孤立性阴茎淋巴水肿的最后一线治疗方法,在这些情况下,手术可以作为药物治疗的辅助手段。