Zhou Yanming, Sui Chengjun, Li Bin, Kan Tong, Yang Jiamei, Wu Mengchao
Department of Hepato-Biliary-Pancreato-Vascular Surgery, The First Affiliated Hospital of Xiamen University, China.
ANZ J Surg. 2011 Dec;81(12):895-9. doi: 10.1111/j.1445-2197.2010.05605.x. Epub 2011 Jan 7.
Right or left trisectionectomy represents the most extensive and difficult type of hepatic resection, and carries an unfavourably high morbidity and mortality. This retrospective study aimed to evaluate the safety and efficacy of trisectionectomy for hepatocellular carcinoma (HCC).
From January 2000 to December 2008, 35 patients with HCC were treated with trisectionectomy. The treatment outcomes of these patients were retrospectively analysed.
Twenty-three right and 12 left trisectionectomies were performed. The overall operative morbidity and mortality were 42.8% (n= 15) and 2.8% (n= 1), respectively. The 1-, 3-, and 5-year overall survival rates were 82.9%, 51.4% and 23.8%, while the 1-, 3- and 5-year disease-free survival rates were 71.4%, 42.9% and 12.9%, respectively.
With careful patient selection and meticulous surgical technique, trisectionectomy can be performed safely and is associated with long-term survival in a subset of patients with HCC.
右半肝或左半肝三叶切除术是肝切除术中范围最广、难度最大的术式,其发病率和死亡率高,预后不佳。本回顾性研究旨在评估肝细胞癌(HCC)三叶切除术的安全性和疗效。
2000年1月至2008年12月,35例HCC患者接受了三叶切除术。对这些患者的治疗结果进行回顾性分析。
实施了23例右半肝三叶切除术和12例左半肝三叶切除术。总体手术发病率和死亡率分别为42.8%(n = 15)和2.8%(n = 1)。1年、3年和5年总生存率分别为82.9%、51.4%和23.8%,而1年、3年和5年无病生存率分别为71.4%、42.9%和12.9%。
通过仔细的患者选择和精细的手术技术,三叶切除术可以安全实施,并且部分HCC患者可实现长期生存。