一名卵巢癌患者在接受高剂量卡铂和粒细胞巨噬细胞集落刺激因子（GM-CSF）治疗后发生的中性粒细胞减少性小肠结肠炎。
Neutropenic enterocolitis in a patient with ovarian cancer after treatment with high-dose carboplatin and granulocyte macrophage-colony stimulating factor (GM-CSF).
作者信息
Vlasveld L T, Ten Bokkel Huinink W W, Rodenhuis S
机构信息
Department of Internal Medicine, The Netherlands Cancer Institute, Amsterdam.
出版信息
Neth J Med. 1990 Oct;37(3-4):158-61.
PMID:2250761
Abstract
A 50-yr-old women is described with relapsed ovarian cancer. She developed neutropenic enterocolitis after treatment with high-dose carboplatin (1000 mg/m2) and granulocyte macrophage-colony stimulating factor (GM-CSF). The clinical features and the pathogenesis of neutropenic enterocolitis are discussed. This case is the first report of neutropenic enterocolitis associated with the treatment of carboplatin.
摘要
一名50岁复发性卵巢癌女性患者被报道。她在接受高剂量卡铂（1000mg/m²）和粒细胞巨噬细胞集落刺激因子（GM-CSF）治疗后发生了中性粒细胞减少性小肠结肠炎。文中讨论了中性粒细胞减少性小肠结肠炎的临床特征和发病机制。该病例是首例与卡铂治疗相关的中性粒细胞减少性小肠结肠炎的报道。
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