Department of Psychological Medicine, University of Otago, New Zealand.
Aust N Z J Psychiatry. 2012 Apr;46(4):317-26. doi: 10.1177/0004867411428101. Epub 2012 Jan 5.
To identify interventions that improve medication adherence in bipolar disorder.
A review of the literature from 2004 to 2011 was conducted using Medline and manual searching.
Eleven studies were identified as meeting inclusion criteria. Five studies demonstrated improved medication adherence. No characteristics of the interventions, clinical characteristics of the groups or methodological factors distinguished those psychosocial interventions that demonstrated improvement from those that did not.
While only a few interventions improved adherence, most improved clinical outcomes. Issues were also identified about the way in which adherence is defined. It is proposed that incorporating patient preferences into measures of adherence within the context of a disorder-specific psychosocial intervention may provide an approach that demonstrates both improved adherence and improved clinical outcomes. However this requires further research.
确定改善双相情感障碍患者药物依从性的干预措施。
使用 Medline 和手动搜索对 2004 年至 2011 年的文献进行了回顾。
确定了 11 项符合纳入标准的研究。五项研究显示出改善的药物依从性。干预措施的特征、组的临床特征或方法学因素都没有区分出那些表现出改善的心理社会干预措施和那些没有改善的措施。
虽然只有少数干预措施改善了依从性，但大多数都改善了临床结果。在定义依从性的方式上也存在问题。有人提出，在特定于疾病的心理社会干预措施的背景下，将患者的偏好纳入依从性的衡量标准，可能提供一种既改善依从性又改善临床结果的方法。但这需要进一步的研究。
