Department of Public Health and Community Medicine, Section of Psychiatry, InterUniversity Centre for Behavioural Neurosciences, University of Verona, Verona, Italy.
Acta Psychiatr Scand. 2012 Nov;126(5):363-76. doi: 10.1111/j.1600-0447.2012.01864.x. Epub 2012 Apr 17.
To explore linguistic abilities in schizophrenia and bipolar disorder. Specifically, the aims of this study were to: i) investigate microlinguistic (lexicon, morphology, syntax) and macrolinguistic (discourse coherence, pragmatics) dimensions of speech production and ii) evaluate syntactic comprehension skills in both schizophrenia and bipolar disorder.
Linguistic performance of 30 Italian-speaking patients with schizophrenia, 30 participants with bipolar disorder and 30 healthy controls comparable for age and educational level has been assessed using a story-telling task and a computer-based test of syntactic comprehension.
In narrative production, compared with healthy participants, those with schizophrenia had slight problems in speech rate and deficits at both local and global discourse coherence, whereas patients with bipolar disorder showed reduced mean length of utterance. As regards syntactic comprehension, both groups of patients collected more grammatical errors than controls, but they differed with regard to the number and kind of grammatical construction they missed.
Linguistic deficits have been detected in both groups of patients, being, however, more severe and generalized in schizophrenia than in bipolar disorder. Such results help us in improving our understanding of the potential psychopathological overlapping between these disorders.
探索精神分裂症和双相情感障碍患者的语言能力。具体而言，本研究旨在：i）研究言语产生的微观语言（词汇、形态、语法）和宏观语言（语篇连贯性、语用学）维度，以及 ii）评估精神分裂症和双相情感障碍患者的句法理解技能。
使用讲故事任务和基于计算机的句法理解测试，评估了 30 名意大利语精神分裂症患者、30 名双相情感障碍患者和 30 名年龄和教育程度相匹配的健康对照组的语言表现。
在叙事产生方面，与健康参与者相比，精神分裂症患者的言语速度稍慢，局部和全局语篇连贯性均存在缺陷，而双相情感障碍患者的平均话语长度较短。在句法理解方面，两组患者的语法错误都比对照组多，但他们在错过的语法结构的数量和类型上存在差异。
在两组患者中都发现了语言缺陷，但在精神分裂症中比在双相情感障碍中更为严重和普遍。这些结果有助于我们更好地理解这些疾病之间潜在的精神病理学重叠。
