Cardiac Arrhythmia and Syncope Center, Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
J Cardiovasc Electrophysiol. 2012 Sep;23(9):1024-7. doi: 10.1111/j.1540-8167.2012.02305.x. Epub 2012 Apr 17.
Vasodepressor Cough Syncope. Cough syncope is classified among the neural-reflex "situational" faints, but whether the clinical consequences in affected individuals result from reflex triggered bradyarrhythmia or vasodepressor-induced hypotension, or both, is often unknown. In this report we describe findings in a patient with a clinical history consistent with cough syncope, and in whom documented multiple asystolic spells were at first believed to be responsible for symptoms. However, pacemaker therapy initiated at an outside facility failed to suppress symptoms, and subsequent referral for more detailed autonomic study revealed the asystole to be due to sleep apnea, whereas cough-induced vasodepressor hypotension was the basis of syncope in this individual; the latter provided a pathophysiologic target for prevention of recurring symptoms. (J Cardiovasc Electrophysiol, Vol. 23, pp. 1024-1027, September 2012).
血管抑制性咳嗽晕厥。咳嗽晕厥属于神经反射“情境性”晕厥，但是否受影响个体的临床后果是由反射触发的心动过缓、血管抑制性低血压或两者共同引起，往往并不清楚。本报告描述了一位临床表现符合咳嗽晕厥的患者的发现，在该患者中，记录到多次停搏性发作，起初被认为是症状的原因。然而，在外部机构启动的起搏器治疗未能抑制症状，随后进行更详细的自主神经研究显示，停搏是由睡眠呼吸暂停引起的，而咳嗽引起的血管抑制性低血压是该个体晕厥的基础；后者为预防症状复发提供了病理生理靶标。（《心血管电生理学杂志》，第 23 卷，第 1024-1027 页，2012 年 9 月）。
