Faculty of Chemistry, Jagiellonian University, Kraków, Poland.
Curr Pharm Des. 2012;18(18):2591-606. doi: 10.2174/138161212800492840.
The properties of heparin, a key anticoagulant, are reviewed. The important issues in heparinotherapy, i.e., reaching quick anticoagulant effect, maintaining therapeutic level of anticoagulation, heparin inhibition and non-invasive heparin formulations have been reviewed and discussed, with the focus on the role of polymeric substances in the proposed solutions.
肝素是一种关键的抗凝剂，本文对其性质进行了综述。讨论和回顾了肝素治疗中的重要问题，即达到快速抗凝效果、维持抗凝治疗水平、肝素抑制和非侵入性肝素制剂，重点介绍了聚合物物质在提出的解决方案中的作用。
