Papaian L P, Golovina O G
Ter Arkh. 1990;62(7):86-92.
Abnormalities of platelet and plasma Willebrand's factor produce noticeable effects on the clinico-laboratory manifestations of Willebrand's disease. This is confirmed by more pronounced gravity of the hemorrhagic syndrome, the lack of the correcting effect in response to physiological conditions (pregnancy) and administration of DDAVP in contrast to beneficial effect seen in patients with normal content of Willebrand's factor in platelets.
血小板和血浆血管性血友病因子异常对血管性血友病的临床实验室表现产生显著影响。出血综合征更为严重、对生理状态（妊娠）无纠正作用以及给予去氨加压素无有益效果（与血小板中血管性血友病因子含量正常的患者所见的有益效果形成对比），均证实了这一点。
