Anesäter Erik, Borgquist Ola, Torbrand Christian, Roupé K Markus, Ingemansson Richard, Lindstedt Sandra, Malmsjö Malin
Lund University and Skåne University Hospital, Lund, Sweden.
Surg Innov. 2013 Feb;20(1):74-80. doi: 10.1177/1553350612444169. Epub 2012 Apr 18.
There are increasing reports of serious complications and deaths associated with negative pressure wound therapy (NPWT). Bleeding may occur when NPWT is applied to a wound with exposed blood vessels. Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel in the wound bed during NPWT.
Wounds were created over the femoral artery in the groin of 8 pigs. Rigid discs were inserted. Wound bed pressures and arterial blood flow were measured during NPWT.
Pressure transduction to the wound bed was similar for control wounds and wounds with discs. Blood flow through the femoral artery decreased in control wounds. When a disc was inserted, the blood flow was restored.
NPWT causes hypoperfusion in the wound bed tissue, presumably as a result of mechanical deformation. The insertion of a rigid barrier alleviates this effect and restores blood flow.
与负压伤口治疗(NPWT)相关的严重并发症和死亡报告日益增多。当NPWT应用于有暴露血管的伤口时可能会发生出血。在伤口中插入刚性圆盘可能会保护这些结构。作者研究了刚性圆盘对NPWT期间伤口床组织压力和通过伤口床中一条大血管的血流的影响。
在8头猪腹股沟的股动脉上方制造伤口。插入刚性圆盘。在NPWT期间测量伤口床压力和动脉血流。
对照伤口和有圆盘的伤口向伤口床的压力传导相似。对照伤口中通过股动脉的血流减少。当插入圆盘时,血流恢复。
NPWT导致伤口床组织灌注不足,推测是机械变形的结果。插入刚性屏障可减轻这种影响并恢复血流。