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左炔诺孕酮宫内节育器(LNG-IUS,曼月乐®)联合子宫内膜消融术治疗月经过多的疗效评估

An evaluation of the simultaneous use of the levonorgestrel-releasing intrauterine device (LNG-IUS, Mirena®) combined with endometrial ablation in the management of menorrhagia.

作者信息

Vaughan D, Byrne P

机构信息

Department of Gynaecology, Beaumont Hospital, Dublin, Ireland.

出版信息

J Obstet Gynaecol. 2012 May;32(4):372-4. doi: 10.3109/01443615.2012.666581.

DOI:10.3109/01443615.2012.666581
PMID:22519484
Abstract

The objective of our study was to document the efficacy and possible complications in women who were treated for menorrhagia with the simultaneous use of endometrial ablation and the levonorgestrel-releasing intrauterine device. Women were offered this combined treatment if they complained of menorrhagia and needed contraception. A structured questionnaire was mailed to 150 women who had undergone this combined treatment; 105 (70%) returned a completed questionnaire. The mean duration of follow-up was 25 months (range 6-54 months). Following treatment, 53 women (50.5%) described their periods as being lighter than normal and 49 (46%) had become amenorrhoeic. Overall, 101 (96%) stated that they were satisfied with the treatment. Of the women, 95 (90.5%) said that the treatment had been a 'complete success'; eight (7.6%) 'partly successful' and two women (1.9%) said the treatment had been a 'failure'. One woman subsequently required a hysterectomy. This observational study supports the hypothesis that combined endometrial ablation and insertion of a levonorgestrel-releasing intrauterine device is an effective treatment for menorrhagia and has some advantages when compared with the individual use of these treatments.

摘要

我们研究的目的是记录同时使用子宫内膜切除术和左炔诺孕酮宫内节育器治疗月经过多的女性的疗效及可能出现的并发症。如果女性主诉月经过多且需要避孕,会为她们提供这种联合治疗。向150名接受过这种联合治疗的女性邮寄了一份结构化问卷;105名(70%)女性返回了完整的问卷。平均随访时间为25个月(范围6 - 54个月)。治疗后,53名女性(50.5%)表示她们的月经量比正常时少,49名(46%)出现闭经。总体而言,101名(96%)表示对治疗满意。在这些女性中,95名(90.5%)称治疗“完全成功”;8名(7.6%)“部分成功”,2名女性(1.9%)称治疗“失败”。一名女性随后需要进行子宫切除术。这项观察性研究支持了这样一种假设,即子宫内膜切除术和左炔诺孕酮宫内节育器联合使用是治疗月经过多的有效方法,与单独使用这些治疗方法相比具有一些优势。

相似文献

1
An evaluation of the simultaneous use of the levonorgestrel-releasing intrauterine device (LNG-IUS, Mirena®) combined with endometrial ablation in the management of menorrhagia.左炔诺孕酮宫内节育器(LNG-IUS,曼月乐®)联合子宫内膜消融术治疗月经过多的疗效评估
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引用本文的文献

1
Hysterectomy Rate Following Endometrial Ablation in Ontario: A Cohort Analysis of 76,446 Patients.安大略省子宫内膜切除术后的子宫切除率:对76446例患者的队列分析。
Facts Views Vis Obgyn. 2024 Sep;16(3):311-316. doi: 10.52054/FVVO.13.3.028.
2
Variation of outcome reporting in studies of interventions for heavy menstrual bleeding: a systematic review.月经过多干预研究中结果报告的差异:一项系统评价
Facts Views Vis Obgyn. 2022 Sep;14(3):205-218. doi: 10.52054/FVVO.14.3.030.
3
Late-onset endometrial ablation failure.迟发性子宫内膜消融失败。
Case Rep Womens Health. 2017 Jul 12;15:11-28. doi: 10.1016/j.crwh.2017.07.001. eCollection 2017 Jul.
4
Endometrial ablation for heavy menstrual bleeding.子宫内膜去除术治疗月经过多。
Womens Health (Lond). 2016 Jan;12(1):45-52. doi: 10.2217/whe.15.86. Epub 2016 Jan 12.