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纵向顺应性聚四氟乙烯血管移植物在绵羊动静脉内瘘模型中的性能

Performance of a longitudinally compliant PTFE vascular prosthesis in an ovine A-V fistula model.

作者信息

Kenney D A, Tu R, Peterson R C, Lu C L

机构信息

Riverside Community Hospital, Department of Surgery, California.

出版信息

ASAIO Trans. 1990 Jul-Sep;36(3):M761-3.

PMID:2252804
Abstract

Nine chronic implants of 6 mm diameter vascular grafts were performed in an ovine model to compare the performance of the longitudinally compliant Ultraflex PTFE-Plus vascular prosthesis with that of the Gore-Tex reinforced expanded polytetra fluoroethylene (PTFE) graft. Implants were performed in the sheep neck as right carotid to left jugular arterio-venous (A-V) grafts. Grafts were explanted after 6 months unless they occluded earlier. The Ultraflex graft demonstrated superior handling characteristics during implant. Patency rate at 6 months was 60% (three of five) for the Ultraflex graft (experimental graft by Baxter Edwards, CVS Division, Irvine, CA), and 25% (one of four) for the Gore-Tex graft (WL Gore & Associates, Inc., Flagstaff, AZ). The Gore-Tex prosthesis had more calcification of the graft wall.

摘要

在绵羊模型中植入了9个直径为6毫米的慢性血管移植物,以比较纵向顺应性的Ultraflex PTFE-Plus血管假体与Gore-Tex增强型膨体聚四氟乙烯(PTFE)移植物的性能。在绵羊颈部进行植入,作为右颈动脉至左颈静脉的动静脉(A-V)移植物。除非移植物提前闭塞,否则在6个月后将其取出。Ultraflex移植物在植入过程中表现出更好的操作特性。Ultraflex移植物(由加利福尼亚州欧文市CVS部门的百特爱德华兹公司生产的实验性移植物)6个月时的通畅率为60%(5个中有3个),而Gore-Tex移植物(亚利桑那州弗拉格斯塔夫的WL Gore & Associates公司生产)的通畅率为25%(4个中有1个)。Gore-Tex假体的移植物壁钙化更多。

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