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体外受精后高凝状态、活化蛋白C抵抗及制动导致的颈静脉血栓形成

[Jugular vein thrombosis caused by hypercoagulability following in-vitro fertilization-activated protein C resistance and immobilization].

作者信息

Stölzel K, Jovanovic S, Albers A E

机构信息

Hals-Nasen-Ohren-Klinik, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany.

出版信息

HNO. 2013 Mar;61(3):250-5. doi: 10.1007/s00106-011-2460-3.

DOI:10.1007/s00106-011-2460-3
PMID:22532279
Abstract

Jugular vein thrombosis (JVT) is extremely difficult to diagnose clinically because of its rarity, the wide range of possible symptoms and the variety of differential diagnoses. A rapid diagnosis is important in order to avoid or prevent imminent life-threatening complications. This study reports a clinical case of extensive JVT due to increased thrombophilia in conjunction with ovarian hyperstimulation syndrome (OHSS) after in vitro fertilization, increased APC resistance and immobilization. It also discusses the current literature that forms the basis for recommendations regarding the diagnosis, therapy and interdisciplinary management.

摘要

颈静脉血栓形成(JVT)在临床上极难诊断,因其罕见、可能出现的症状范围广泛且鉴别诊断多样。快速诊断对于避免或预防即将危及生命的并发症很重要。本研究报告了一例体外受精后因血栓形成倾向增加合并卵巢过度刺激综合征(OHSS)、活化蛋白C抵抗增加和制动导致的广泛JVT临床病例。它还讨论了构成诊断、治疗和多学科管理建议基础的当前文献。

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HNO. 2013 Mar;61(3):250-5. doi: 10.1007/s00106-011-2460-3.
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引用本文的文献

1
[Diagnosis and treatment of jugular vein thrombosis].[颈静脉血栓形成的诊断与治疗]
HNO. 2019 Jun;67(6):469-482. doi: 10.1007/s00106-019-0673-z.

本文引用的文献

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Basic mechanisms and pathogenesis of venous thrombosis.静脉血栓形成的基本机制与发病机制。
Blood Rev. 2009 Sep;23(5):225-9. doi: 10.1016/j.blre.2009.07.002.
2
Lemierre's syndrome: A systematic review.勒米尔综合征:一项系统评价。
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A risk score for the management of pregnant women with increased risk of venous thromboembolism: a multicentre prospective study.用于管理静脉血栓栓塞风险增加的孕妇的风险评分:一项多中心前瞻性研究。
Br J Haematol. 2009 Jun;145(6):825-35. doi: 10.1111/j.1365-2141.2009.07698.x. Epub 2009 Apr 15.
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Prophylaxis of VTE in women - during assisted reproductive techniques.女性在辅助生殖技术期间静脉血栓栓塞的预防
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Tumor-derived microvesicles in sera of patients with head and neck cancer and their role in tumor progression.头颈部癌患者血清中肿瘤来源的微泡及其在肿瘤进展中的作用。
Head Neck. 2009 Mar;31(3):371-80. doi: 10.1002/hed.20968.
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Virchow and his triad: a question of attribution.魏尔啸及其三联征:归因问题。
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Coagulation factor V and thrombophilia: background and mechanisms.凝血因子V与血栓形成倾向:背景与机制
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[Internal jugular vein thrombosis as a paraneoplastic syndrome].[颈内静脉血栓形成作为一种副肿瘤综合征]
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Septic thrombophlebitis: diagnosis and management.脓毒性血栓性静脉炎:诊断与管理
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