Huan Lawrence, Jetly Rachna, Kandil Emad
Department of Surgery, Tulane University School of Medicine, New Orleans, USA.
J La State Med Soc. 2012 Jan-Feb;164(1):26-30.
Paragangliomas are tumors of the sympathetic and parasympathetic paraganglia. While most paraganglioma are of parasympathetic origin and present as benign palpable masses of the neck, sympathetic paraganglioma are often secretory, presenting with symptoms related to excess catecholamines. Such symptoms include hypertension, headache, palpitations, and diaphoresis. Most sympathetic paraganglioma form within the adrenal medulla, the largest sympathetic paraganglia, and are commonly known as pheochromocytomas. However, sympathetic paragangliomas may present extra-adrenally, carrying a significantly higher risk of malignancy. In this manuscript, we examine a case of a young man with an extra-adrenal sympathetic paraganglioma of the Organ of Zuckerkandl. Furthermore, we discuss appropriate diagnostic workup and treatment of pheochromocytomas and sympathetic paragangliomas.
副神经节瘤是交感神经和副交感神经节的肿瘤。虽然大多数副神经节瘤起源于副交感神经，表现为颈部可触及的良性肿块，但交感神经副神经节瘤通常具有分泌功能，表现出与儿茶酚胺过多相关的症状。这些症状包括高血压、头痛、心悸和多汗。大多数交感神经副神经节瘤形成于肾上腺髓质（最大的交感神经节）内，通常被称为嗜铬细胞瘤。然而，交感神经副神经节瘤也可能出现在肾上腺外，恶性风险显著更高。在本手稿中，我们研究了一例患有祖克坎德尔器肾上腺外交感神经副神经节瘤的年轻男性病例。此外，我们还讨论了嗜铬细胞瘤和交感神经副神经节瘤的适当诊断检查和治疗方法。
