Ben-Jebria A, Full A P, DeMaria D D, Ball B A, Ultman J S
Department of Chemical Engineering, Pennsylvania State University, University Park 16802.
Environ Res. 1990 Dec;53(2):119-34. doi: 10.1016/s0013-9351(05)80114-8.
The absorption of sulfur dioxide (SO2) into excised porcine tracheae was characterized by a step-response experiment in which SO2 outlet concentration was monitored during the 30-min interval following introduction of inlet concentrations of 0.1-0.6 ppm at steady air flows of 2.7-11.0 liter/min. These data were analyzed with a diffusion-reaction theory incorporating three independent parameters--a gas phase mass transfer coefficient, kg, a tissue phase diffusivity x solubility product, D(alpha RT)2, and a tissue phase reaction constant, kr. While single values of 17 sec-1 for kr and 0.28 m2/sec for D(alpha RT)2 were sufficient to simulate all the data, it was necessary to vary kg from a 0.032 to 0.121 m/sec in direct proportion to the gas flow. Based on these parameter values, gas phase resistance accounts for about one-fourth of the total resistance to absorption in gas and tissue phases combined. All three parameters were independent of inlet concentration, implying that diffusion, solubility, and irreversible reaction of SO2 in tissue are all linear processes.
通过阶跃响应实验对二氧化硫（SO₂）在离体猪气管中的吸收进行了表征。在该实验中，在稳定气流为2.7 - 11.0升/分钟的情况下，引入0.1 - 0.6 ppm的入口浓度后，在30分钟的时间间隔内监测SO₂出口浓度。利用包含三个独立参数的扩散 - 反应理论对这些数据进行了分析，这三个参数分别是气相传质系数kg、组织相传质系数x溶解度乘积D(αRT)²以及组织相反应常数kr。虽然kr的单一值为17秒⁻¹以及D(αRT)²的单一值为0.28平方米/秒足以模拟所有数据，但有必要使kg在0.032至0.121米/秒之间变化，且与气流成正比。基于这些参数值，气相阻力约占气相和组织相结合吸收总阻力的四分之一。所有这三个参数均与入口浓度无关，这意味着SO₂在组织中的扩散、溶解和不可逆反应均为线性过程。
