Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China.
Evid Based Complement Alternat Med. 2012;2012:417387. doi: 10.1155/2012/417387. Epub 2012 Mar 28.
Objective. The aim of this overview was to evaluate and summarize Cochrane reviews of traditional Chinese herbal products (TCHPs) as the treatment for coronary heart disease (CHD). Methods. We searched the Cochrane Database that was concerned with the effectiveness of TCHPs for CHD. We also searched the Cochrane Central Register of Controlled Trials. Reviews and primary studies of TCHP as the treatment of any type of CHD were included. Data were extracted according to predefined inclusion criteria by two independent reviewers. Results. Six Cochrane reviews were included. They related to a wide range of TCHPs for different types of CHD. Four reviews were concerned with angina pectoris (unstable or stable), one review was concerned with heart failure, and for acute myocardial infarction. No reviews concluded that TCHPs were definitely effective for CHD because of the weak evidence. Eight primary studies were TCHPs from CHD. These studies also maybe result in bias, but better than before. Conclusion. Several Cochrane reviews of TCHPs for the treatment of different types of CHD have recently been published. None of these reviews got definite conclusion favoring the effectiveness of TCHPs due to the weak evidence. With the improved quality of the new registered RCTs. The potential role of TCHPs in treating CHD is anticipated to be detected.
目的。本综述旨在评估和总结 Cochrane 对中药治疗冠心病 (CHD) 的评价。
方法。我们检索了 Cochrane 数据库中关于 TCHP 治疗 CHD 的有效性的信息。我们还检索了 Cochrane 对照试验中心注册库。纳入 TCHP 治疗任何类型 CHD 的综述和原始研究。两名独立评审员根据预先设定的纳入标准提取数据。
结果。共纳入 6 项 Cochrane 综述。它们涉及不同类型 CHD 的多种 TCHP。其中 4 项综述涉及不稳定或稳定型心绞痛，1 项综述涉及心力衰竭，还有 1 项综述涉及急性心肌梗死。由于证据薄弱，没有一项综述得出 TCHP 对 CHD 肯定有效的结论。8 项原始研究为 CHD 的 TCHP。这些研究也可能存在偏倚，但比以前有所改善。
结论。最近发表了几篇关于 TCHP 治疗不同类型 CHD 的 Cochrane 综述。由于证据薄弱，这些综述均未得出 TCHP 有效的明确结论。随着新注册 RCT 质量的提高，预计 TCHP 在治疗 CHD 中的潜在作用将被发现。
