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[接受抗凝或抗血小板治疗的患者拔牙后使用氰基丙烯酸酯涂层黏附膜进行局部止血]

[Local haemostasis with an adhesive cyanoacrylate-coated membrane following tooth extraction in patients under anticoagulant or anti-platelet therapy].

作者信息

Lesca C, Boumendjel S, Boumendjel M, Hefied M, Ben Ismail S, Bonnefous D

机构信息

Service de Stomatologie et Chirurgie Maxillo-Faciale, Hôpital André-Mignot, Centre Hospitalier de Versailles, 177 rue de Versailles, 78157 Le Chesnay cedex, France.

出版信息

Rev Stomatol Chir Maxillofac. 2012 Jun;113(3):143-7. doi: 10.1016/j.stomax.2012.02.006. Epub 2012 Apr 25.

DOI:10.1016/j.stomax.2012.02.006
PMID:22537515
Abstract

OBJECTIVE

Assessment of a local hemostasis with a compressive, extemporaneous gutter glued to the alveolar crest after tooth avulsion in patients under anticoagulant and/or platelet aggregation inhibitors, and economical impact of this technique.

MATERIAL AND METHOD

Ninety-seven tooth extractions were performed in patients under AVK and/or anti-platelet drugs. The interventions were consecutive and concerned 251 teeth (138 different alveolar sites). The extraction alveolus was protected by an absorbable oxycellulose membrane coated with sterilized cyanoacrylate adhesive for medical use. This procedure was used with all patients, whatever the hemorrhagic risk (the only inclusion criterion was INR less than 4 for patients under AVK). All procedures were performed under local anesthesia.

RESULTS

There was one hemorrhagic complication (0.72%) due to mechanical gutter destruction by an antagonist tooth. The adhesive did not run, there was no tissue necrosis, and no wound infection requiring gutter removal.

DISCUSSION

This local hemostasis procedure is reliable. It may be an alternative to substitution of heparin, without or with hospitalization. This procedure, requiring modification of treatment, greatly decreases healthcare costs. Contra-indications include the presence of an antagonist tooth harmful for the gutter, and patients with impaired consciousness or tongue dyspraxia.

摘要

目的

评估在接受抗凝剂和/或血小板聚集抑制剂治疗的患者牙齿脱落后,使用一种临时制作的、粘贴于牙槽嵴的压迫性局部止血方法及其经济影响。

材料与方法

对接受维生素K拮抗剂(AVK)和/或抗血小板药物治疗的患者进行了97次拔牙。干预是连续进行的,涉及251颗牙齿(138个不同的牙槽部位)。拔牙后的牙槽用涂有医用灭菌氰基丙烯酸酯粘合剂的可吸收氧化纤维素膜保护。无论出血风险如何,所有患者均采用此方法(对于接受AVK治疗的患者,唯一的纳入标准是国际标准化比值(INR)小于4)。所有操作均在局部麻醉下进行。

结果

因对颌牙破坏止血沟导致1例出血并发症(0.72%)。粘合剂未外溢,无组织坏死,也无需要去除止血沟的伤口感染。

讨论

这种局部止血方法可靠。它可能是替代肝素的一种选择,无论是否需要住院。这种需要调整治疗的方法可大幅降低医疗成本。禁忌症包括存在对止血沟有害的对颌牙,以及意识障碍或舌运动障碍患者。

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