Division of Acupuncture and Chinese Traumatology, Department of Traditional Chinese Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
J Altern Complement Med. 2012 May;18(5):509-12. doi: 10.1089/acm.2011.0292. Epub 2012 Apr 26.
A case is presented that illustrates the potential effect of traditional Chinese medicine (TCM) herbal formulas on treatment for unilateral pleural effusion secondary to congestive heart failure (CHF).
A 79-year-old woman experienced episodic dyspnea with unilateral pleural effusion for 2 years. Thoracocentesis with pleural fluid analysis revealed no infection, tuberculosis, or malignancy. She had received conventional treatment for CHF but the symptoms persisted. Therefore, she visited the authors' TCM clinic for help.
This patient was treated with TCM herbal granules including Shengmaisan, Xiebaisan, and Tinglizi, 3 times a day for 4 weeks. The daily dosage was adjusted on the basis of the patient's clinical response and her follow-up chest x-ray studies. After 8 months of treatment, her symptoms improved and the pleural effusion showed significant regression.
It is suggested that TCM herbal formulas could play an important role in preventing the progression of unilateral pleural effusion secondary to CHF, in case of poor response to conservative treatment. Additional studies about the mechanism of action of the medication involved are warranted.
本病例说明了中药方剂对充血性心力衰竭(CHF)继发单侧胸腔积液治疗的潜在影响。
一位 79 岁女性,2 年来出现间歇性呼吸困难伴单侧胸腔积液。胸腔穿刺抽取胸腔积液分析未发现感染、结核或恶性肿瘤。她接受了 CHF 的常规治疗,但症状持续存在。因此,她前往作者的中医诊所寻求帮助。
该患者接受了包括升麻散、泻白散和荜茇散在内的中药颗粒治疗,每日 3 次,持续 4 周。根据患者的临床反应和随访胸部 X 线研究调整每日剂量。治疗 8 个月后,她的症状改善,胸腔积液明显消退。
建议在保守治疗反应不佳的情况下,中药方剂可能在预防 CHF 继发单侧胸腔积液进展方面发挥重要作用。需要进一步研究药物作用机制。