Department of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany.
Int J Psychiatry Clin Pract. 2012 Jun;16(2):77-84. doi: 10.3109/13651501.2012.667114. Epub 2012 Apr 30.
Anxiety disorders are frequently under-diagnosed conditions in primary care, although they can be managed effectively by general practitioners.
This paper is a short and practical summary of the World Federation of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety disorders, obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) for the treatment in primary care. The recommendations were developed by a task force of 30 international experts in the field and are based on randomized controlled studies.
First-line pharmacological treatments for these disorders are selective serotonin reuptake inhibitors (for all disorders), serotonin-norepinephrine reuptake inhibitors (for some) and pregabalin (for generalized anxiety disorder only). A combination of medication and cognitive behavior/exposure therapy was shown to be a clinically desired treatment strategy.
This short version of an evidence-based guideline may improve treatment of anxiety disorders, OCD, and PTSD in primary care.
焦虑障碍在初级保健中经常被漏诊，但它们可以被全科医生有效地治疗。
本文是世界生物精神病学联合会（WFSBP）关于焦虑障碍、强迫症（OCD）和创伤后应激障碍（PTSD）的药物治疗指南的简短实用总结，适用于初级保健中的治疗。该建议由 30 名该领域的国际专家组成的工作组制定，基于随机对照研究。
这些疾病的一线药物治疗包括选择性 5-羟色胺再摄取抑制剂（适用于所有疾病）、5-羟色胺-去甲肾上腺素再摄取抑制剂（适用于某些疾病）和普瑞巴林（仅用于广泛性焦虑障碍）。药物治疗联合认知行为/暴露疗法是一种理想的临床治疗策略。
本循证指南的简短版本可能会改善初级保健中焦虑障碍、强迫症和创伤后应激障碍的治疗。
