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焦虑障碍、强迫症和创伤后应激障碍的药物治疗指南。

Guidelines for the pharmacological treatment of anxiety disorders, obsessive-compulsive disorder and posttraumatic stress disorder in primary care.

机构信息

Department of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany.

出版信息

Int J Psychiatry Clin Pract. 2012 Jun;16(2):77-84. doi: 10.3109/13651501.2012.667114. Epub 2012 Apr 30.

Abstract

OBJECTIVE

Anxiety disorders are frequently under-diagnosed conditions in primary care, although they can be managed effectively by general practitioners.

METHODS

This paper is a short and practical summary of the World Federation of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety disorders, obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) for the treatment in primary care. The recommendations were developed by a task force of 30 international experts in the field and are based on randomized controlled studies.

RESULTS

First-line pharmacological treatments for these disorders are selective serotonin reuptake inhibitors (for all disorders), serotonin-norepinephrine reuptake inhibitors (for some) and pregabalin (for generalized anxiety disorder only). A combination of medication and cognitive behavior/exposure therapy was shown to be a clinically desired treatment strategy.

CONCLUSIONS

This short version of an evidence-based guideline may improve treatment of anxiety disorders, OCD, and PTSD in primary care.

摘要

目的

焦虑障碍在初级保健中经常被漏诊,但它们可以被全科医生有效地治疗。

方法

本文是世界生物精神病学联合会(WFSBP)关于焦虑障碍、强迫症(OCD)和创伤后应激障碍(PTSD)的药物治疗指南的简短实用总结,适用于初级保健中的治疗。该建议由 30 名该领域的国际专家组成的工作组制定,基于随机对照研究。

结果

这些疾病的一线药物治疗包括选择性 5-羟色胺再摄取抑制剂(适用于所有疾病)、5-羟色胺-去甲肾上腺素再摄取抑制剂(适用于某些疾病)和普瑞巴林(仅用于广泛性焦虑障碍)。药物治疗联合认知行为/暴露疗法是一种理想的临床治疗策略。

结论

本循证指南的简短版本可能会改善初级保健中焦虑障碍、强迫症和创伤后应激障碍的治疗。

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