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患者因素与血糖控制:关联与解释力。

Patient factors and glycaemic control--associations and explanatory power.

机构信息

Steno Health Promotion Centre, Steno Diabetes Centre, Gentofte, Denmark.

出版信息

Diabet Med. 2012 Oct;29(10):e382-9. doi: 10.1111/j.1464-5491.2012.03703.x.

Abstract

AIMS

To investigate the association between glycaemic control and patient socio-demographics, activation level, diabetes-related distress, assessment of care, knowledge of target HbA(1c), and self-management behaviours, and to determine to what extent these factors explain the variance in HbA(1c) in a large Danish population of patients with Type 2 diabetes.

METHODS

Cross-sectional survey and record review of 2045 patients from a specialist diabetes clinic. Validated scales measured patient activation, self-management behaviours, diabetes-related emotional distress, and perceived care. The electronic patient record provided information about HbA(1c), medication, body mass index, and duration of diabetes. Data were analysed using multiple linear regression models with stepwise addition of covariates.

RESULTS

The response rate was 54% (n = 1081). Good glycaemic control was significantly associated with older age, higher education, higher patient activation, lower diabetes-related emotional distress, better diet and exercise behaviours, lower body mass index, shorter duration of disease and knowledge of HbA(1c) targets (P < 0.05 for all). Patient socio-demographics, behaviour; perceptions of care and diabetes distress accounted for 14% of the total variance in HbA(1c) levels (P = 0.0134), but the variance explained was higher for respondents treated with medications other than insulin.

CONCLUSIONS

Our study emphasizes the complex relationships between patient activation, distress and behaviour, specific treatment modalities and glycaemic control. Knowledge of treatment goals, achieving patient activation in coping with diabetes, and lowering disease-related emotional stress are important patient education goals. However, the large unexplained component of HbA(1c) variance highlights the need for more research to understand the mechanisms of glycaemic control.

摘要

目的

调查血糖控制与患者社会人口统计学、激活水平、与糖尿病相关的困扰、护理评估、目标 HbA(1c)的了解以及自我管理行为之间的关系,并确定这些因素在多大程度上解释了 2 型糖尿病患者的 HbA(1c)变异。

方法

对来自专科糖尿病诊所的 2045 名患者进行横断面调查和病历回顾。验证量表测量了患者的激活、自我管理行为、与糖尿病相关的情绪困扰和感知护理。电子患者记录提供了关于 HbA(1c)、药物、体重指数和糖尿病持续时间的信息。使用逐步加入协变量的多元线性回归模型分析数据。

结果

响应率为 54%(n=1081)。良好的血糖控制与年龄较大、教育程度较高、患者激活水平较高、与糖尿病相关的情绪困扰较低、饮食和运动行为较好、体重指数较低、疾病持续时间较短以及对 HbA(1c)目标的了解较高显著相关(所有 P<0.05)。患者的社会人口统计学特征、行为、护理和糖尿病困扰的认知占 HbA(1c)水平总方差的 14%(P=0.0134),但对于接受胰岛素以外药物治疗的患者,解释的方差更高。

结论

我们的研究强调了患者激活、困扰和行为、特定治疗方式和血糖控制之间的复杂关系。了解治疗目标、在应对糖尿病方面实现患者激活以及降低与疾病相关的情绪压力是重要的患者教育目标。然而,HbA(1c)变异的较大未解释部分突出表明需要更多的研究来了解血糖控制的机制。

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