Fraisse P
Service de pneumologie, Nouvel hôpital civil, 1 place de l'Hôpital, Strasbourg cedex, France.
Rev Mal Respir. 2012 Apr;29(4):579-600. doi: 10.1016/j.rmr.2011.07.011. Epub 2012 Mar 27.
Latent tuberculosis infection is a key stage in the natural history of tuberculosis, and provides an important period where strategies to prevent the development of disease may be implemented. The treatment of latent tuberculosis infection is well described in many national guidelines. In this review, we attempt to help pneumonologists to implement these guidelines accurately and appropriately, prescribing preventive treatment when the benefit-risk ratio is optimal, providing treatment most safely, performing therapeutic education and incorporating preventive treatment into the full array of measures against tuberculosis.
潜伏性结核感染是结核病自然史中的关键阶段,为实施预防疾病发展策略提供了重要时期。许多国家指南对潜伏性结核感染的治疗有详尽描述。在本综述中,我们试图帮助肺科医生准确、恰当地实施这些指南,在获益风险比最佳时开具预防性治疗,以最安全的方式提供治疗,开展治疗教育,并将预防性治疗纳入全面的结核病防治措施中。