Fois A M, Pourquier M, Bouisson A M
Laboratoire de Microbiologie, Faculté de Chirurgie Dentaire, Université de Montpellier, France.
J Biol Buccale. 1990 Sep;18(3):169-75.
The pH and lysozyme content of the salivas of 34 patients receiving radiotherapy of the upper respiratory digestive tracts for the treatment of cancer were compared to those of 22 healthy subjects matched for age and gender. After irradiation the salivas of the treated patients had a lower mean pH (p less than 0.001). During radiotherapy no statistically significant changes occurred in the pH or lysozyme rate, but at the beginning of treatment there was an inverse correlation (p less than 0.05) between the increased lysozyme content and the lowered pH. The mean salivary pH and lysozyme rate of 12 patients (35%) initially treated by chemotherapy showed no significant differences from controls. However, the saliva of 21 dentate patients had a mean pH and lysozyme content considerably higher (p less than 0.01) than that of patients without teeth. During radiotherapy there was a statistically significant inverse relationship between the pH of the salivas of the dentate and edentulous groups.
将34例接受上呼吸道消化道癌症放射治疗患者的唾液pH值和溶菌酶含量，与22例年龄和性别相匹配的健康受试者的唾液进行比较。照射后，治疗患者的唾液平均pH值较低（p<0.001）。放疗期间，pH值或溶菌酶率无统计学显著变化，但在治疗开始时，溶菌酶含量增加与pH值降低之间存在负相关（p<0.05）。12例（35%）最初接受化疗的患者的唾液平均pH值和溶菌酶率与对照组无显著差异。然而，21例有牙患者的唾液平均pH值和溶菌酶含量明显高于无牙患者（p<0.01）。放疗期间，有牙组和无牙组唾液的pH值之间存在统计学显著的负相关关系。
