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腰椎神经根病发生的发病率及危险因素特征

Characterization of the incidence and risk factors for the development of lumbar radiculopathy.

作者信息

Schoenfeld Andrew J, Laughlin Matthew, Bader Julia O, Bono Christopher M

机构信息

Department of Orthopaedic Surgery, William Beaumont Army Medical Center, Texas Tech, 5005 N. Piedras Street, El Paso, TX 79920, USA.

出版信息

J Spinal Disord Tech. 2012 May;25(3):163-7. doi: 10.1097/BSD.0b013e3182146e55.

Abstract

STUDY DESIGN

Epidemiological study of a prospectively collected database.

OBJECTIVES

This investigation sought to evaluate the incidence of symptomatic lumbar radiculopathy, and identify risk factors for its development, among individuals serving in the United States military over a 10-year period.

SUMMARY OF BACKGROUND DATA

Risk factors for the development of lumbar radiculopathy are poorly understood and the incidence of this disorder has not been characterized earlier for a young, high-demand population.

METHODS

The Defense Medical Epidemiology Database was queried for the years 2000 to 2009 using the International Classification of Diseases ninth revision code for lumbar radiculopathy (724.4). Overall incidence was determined and multivariate Poisson regression analysis was carried out to identify the influence of risk factors such as age, sex, race, military rank, and branch of service on the development of this condition.

RESULTS

In this population, the overall incidence of lumbar radiculopathy was 4.86 per 1000 person-years. Multivariate Poisson regression analysis showed that female sex, white race, senior positions within the rank structure, and service in the Army, Navy, or Air Force increased the risk of developing lumbar radiculopathy. Servicemembers of 30 years and older were found to have >3 times the risk of developing lumbar radiculopathy when compared with individuals <20.

CONCLUSIONS

The incidence of lumbar radiculopathy in this young, racially diverse, and physically active population is higher than many other degenerative conditions. In this study female sex and white race increased the risk of developing lumbar radiculopathy. However, increasing age seems to be one of the most significant independent factors for developing this disorder.

LEVEL OF EVIDENCE

Level II, prognostic study.

摘要

研究设计

对前瞻性收集的数据库进行的流行病学研究。

目的

本调查旨在评估美国军队服役人员在10年期间症状性腰椎神经根病的发病率,并确定其发病的风险因素。

背景数据总结

腰椎神经根病发病的风险因素了解甚少,且该疾病在年轻、高需求人群中的发病率此前尚未有过描述。

方法

使用国际疾病分类第九版中腰椎神经根病的编码(724.4)查询2000年至2009年的国防医疗流行病学数据库。确定总体发病率,并进行多变量泊松回归分析,以确定年龄、性别、种族、军衔和军种等风险因素对该病发展的影响。

结果

在该人群中,腰椎神经根病的总体发病率为每1000人年4.86例。多变量泊松回归分析表明,女性、白人、军衔结构中的高级职位以及在陆军、海军或空军服役会增加患腰椎神经根病的风险。与20岁以下的个体相比,30岁及以上的军人患腰椎神经根病的风险是其3倍以上。

结论

在这个年轻、种族多样且身体活跃的人群中,腰椎神经根病的发病率高于许多其他退行性疾病。在本研究中,女性和白人种族增加了患腰椎神经根病的风险。然而,年龄增长似乎是患这种疾病最重要的独立因素之一。

证据水平

二级,预后研究。

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