Department of Chemistry, Vanderbilt University, 7300 Stevenson Ctr Ln, Nashville, TN 37235, USA.
Chem Commun (Camb). 2012 Jun 4;48(44):5428-30. doi: 10.1039/c2cc31951a. Epub 2012 Apr 27.
Here we present the development and validation of a flow cytometry-based dopamine transporter (DAT) binding assay that uses antagonist-conjugated quantum dots (QDs). We anticipate that our QD-based assay is of immediate value to the high throughput screening of novel DAT modulators.
在这里,我们介绍了一种基于流式细胞术的多巴胺转运体(DAT)结合分析的开发和验证,该分析使用了与拮抗剂偶联的量子点(QD)。我们预计,我们基于 QD 的分析方法将对新型 DAT 调节剂的高通量筛选具有直接价值。