National Institute for Communicable Diseases, Johannesburg, South Africa.
Clin Infect Dis. 2012 May;54 Suppl 4(Suppl 4):S334-8. doi: 10.1093/cid/cir1017.
Surveillance of human immunodeficiency virus type 1 transmitted drug resistance (TDR) was conducted among pregnant women in South Africa over a 5-year period after the initiation of a large national antiretroviral treatment program. Analysis of TDR data from 9 surveys conducted between 2005 and 2009 in 2 provinces of South Africa suggests that while TDR remains low (<5%) in Gauteng Province, it may be increasing in KwaZulu-Natal, with the most recent survey showing moderate (5%-15%) levels of resistance to the nonnucleoside reverse transcriptase inhibitor drug class.
在南非启动大规模国家抗逆转录病毒治疗项目后，对孕妇中的人类免疫缺陷病毒 1 型传播耐药性（TDR）进行了为期 5 年的监测。对 2005 年至 2009 年在南非 2 个省进行的 9 次调查的 TDR 数据进行分析表明，尽管在豪登省 TDR 仍然较低（<5%），但在夸祖鲁-纳塔尔省可能正在增加，最近的调查显示，对非核苷类逆转录酶抑制剂药物类别的耐药性达到中等水平（5%-15%）。
