Baptist Children's Hospital in Miami, Florida 33176, USA.
Am J Crit Care. 2012 May;21(3):178-83; quiz 184. doi: 10.4037/ajcc2012548.
The incidence of venous thromboembolism in children has increased dramatically, with most cases occurring in children with cancer, surgery, trauma, congenital heart disease, and systemic lupus erythematosus. Early assessment of risk factors present in children would minimize morbidity and mortality from these events.
To evaluate the reliability and validity of a tool for assessing risk for venous thromboembolism in children.
The tool was developed after a review of the literature with assessment of content validity by a multidisciplinary team of experts. Patients' charts were reviewed retrospectively to establish reliability and validity of the tool. A P value less than .05 was considered statistically significant.
Thirty-five charts were assessed for tool validity and were found to be statistically significant for all 3 risk score assessment categories. Logistic regression was used to assess 1001 patients' charts for internal consistency, which was found to be high (χ(2)(5)[n = 1001] = 100.6, P < .001). Results indicated that most patients at risk for venous thromboembolism were between the ages of 13 and 17 years, with females having more than 7 times greater risk than males.
Descriptive statistics show that the assessment tool displays strong reliability and validity. Results validated a significant relationship between the risk score and the incidence of venous thromboembolism. Findings suggest that use of the assessment tool could significantly reduce adverse outcomes associated with venous thromboembolism in children.
儿童静脉血栓栓塞症的发病率显著增加，大多数病例发生在癌症、手术、创伤、先天性心脏病和系统性红斑狼疮患儿中。早期评估患儿存在的危险因素可最大限度地降低这些事件的发病率和死亡率。
评估一种用于评估儿童静脉血栓栓塞症风险的工具的可靠性和有效性。
该工具是在对文献进行回顾的基础上开发的，并由一个多学科专家小组对其内容效度进行评估。回顾性地评估了患者的病历以确定该工具的可靠性和有效性。P 值小于 0.05 被认为具有统计学意义。
对 35 份病历进行了工具有效性评估，发现所有 3 种风险评分评估类别均具有统计学意义。使用逻辑回归评估了 1001 份病历的内部一致性，结果显示一致性较高（χ(2)(5)[n = 1001] = 100.6，P < 0.001）。结果表明，大多数有静脉血栓栓塞风险的患者年龄在 13 至 17 岁之间，女性的风险是男性的 7 倍以上。
描述性统计数据显示，评估工具具有较强的可靠性和有效性。结果验证了风险评分与静脉血栓栓塞发生率之间存在显著关系。研究结果表明，使用评估工具可以显著降低儿童静脉血栓栓塞相关的不良后果。
