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甲基叔丁基醚:近期致癌性研究

MTBE: recent carcinogenicity studies.

作者信息

Burns Kathleen M, Melnick Ronald L

机构信息

Sciencecorps, MA, USA.

出版信息

Int J Occup Environ Health. 2012 Jan-Mar;18(1):66-9. doi: 10.1179/107735212X13293200778947.

Abstract

MTBE, a gasoline oxygenate, has contaminated drinking water sources for many years. Carcinogenicity studies conducted in animals in the 1990s raised concerns of potential human health risks. Recent industry-sponsored studies have confirmed the carcinogenic effects of this agent and have identified additional sites of tumor induction (i.e., brain). However, the petroleum industry has attempted to portray these recent findings as demonstrating either no effect or no concern for humans. Our paper briefly summarizes the new findings and puts into perspective the totality of carcinogenic effects and health risks on this environmental chemical.

摘要

甲基叔丁基醚(MTBE)作为一种汽油中的含氧化合物,多年来已污染了饮用水源。20世纪90年代在动物身上进行的致癌性研究引发了对潜在人类健康风险的担忧。最近由行业赞助的研究证实了该物质的致癌作用,并确定了其他肿瘤诱导部位(即脑部)。然而,石油行业试图将这些最新发现描述为对人类没有影响或无需担忧。我们的论文简要总结了这些新发现,并从整体上审视了这种环境化学物质的致癌作用和健康风险。

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