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法洛四联症早期修复术中肺动脉瓣球囊扩张。

The balloon dilation of the pulmonary valve during early repair of tetralogy of Fallot.

机构信息

Department of Cardiac, Thoracic and Vascular Surgery, Pediatric and Congenital Cardiac Surgery Unit, University of Padua, Padua, Italy.

出版信息

Catheter Cardiovasc Interv. 2012 Nov 15;80(6):915-21. doi: 10.1002/ccd.24349. Epub 2012 May 2.

DOI:10.1002/ccd.24349
PMID:22552947
Abstract

BACKGROUND AND OBJECTIVE

Progressive pulmonary valve (PV) regurgitation leads to right ventricular failure after repair of tetralogy of Fallot (TOF). We sought to evaluate our results with the preservation of the PV in selected patients with TOF.

METHODS

All patients with TOF who were scheduled for PV's preservation between June 2007 and May 2010 were enrolled. Surgical correction involved the combination of early transatrial repair and intraoperative balloon dilation of the PV annulus.

RESULTS

Of 18 patients, 16 (89%) underwent a successful preservation of the PV. Median age at surgery was 3.1 months (range 2.4-4.7 months). Median preoperative PV Z-score was -2.5 (range -1.4 to -3.12) and the median peak right ventricle outflow tract (RVOT) gradient was 80 mm Hg (range 49-90 mm Hg). No procedure-related complications were reported. The size of the PV annulus after the balloon dilation was appropriate for body surface area in all patients. Median follow-up time was 1.4 years (range 0.5-3.3 years). Reoperation was needed in one patient 3 months after repair because of residual subvalvar RVOT obstruction. The remaining 15 patients are alive and well. The median PV Z-score is 0 (range -0.2 to 1). Median peak RVOT gradient is 20 mm Hg (range 12-32 mm Hg). The PV is competent in seven patients; mild PV regurgitation is present in seven patients and moderate in one.

CONCLUSIONS

The integrity of the PV annulus and PV function can be preserved in selected patients during early repair of TOF when using concomitant balloon dilation. The PV preservation will hopefully prevent long-standing RV dysfunction.

摘要

背景与目的

法洛四联症(TOF)修复后,进行性肺动脉瓣(PV)反流可导致右心室衰竭。我们试图评估选择性保留 PV 对 TOF 患者的疗效。

方法

2007 年 6 月至 2010 年 5 月,所有计划行 PV 保留的 TOF 患者均纳入研究。手术矫正包括早期经心房修复和术中 PV 瓣环球囊扩张。

结果

18 例患者中,16 例(89%)成功保留了 PV。手术时中位年龄为 3.1 个月(范围 2.4-4.7 个月)。术前 PVZ 评分中位数为-2.5(范围-1.4 至-3.12),右心室流出道(RVOT)峰值压差中位数为 80mmHg(范围 49-90mmHg)。无手术相关并发症。所有患者的 PV 瓣环直径均与体表面积相匹配。中位随访时间为 1.4 年(范围 0.5-3.3 年)。1 例患者在修复后 3 个月因残余瓣下 RVOT 梗阻而再次手术。其余 15 例患者均存活且状况良好。PVZ 评分中位数为 0(范围-0.2 至 1)。RVOT 峰值压差中位数为 20mmHg(范围 12-32mmHg)。7 例患者的 PV 功能正常,7 例患者轻度反流,1 例患者中度反流。

结论

在早期修复 TOF 时,使用同期球囊扩张可以选择性保留部分患者的 PV 瓣环和 PV 功能。保留 PV 有望防止长期 RV 功能障碍。

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