早产儿视网膜病变的危险因素分析。
Analysis of risk factors for retinopathy of prematurity.
作者信息
Li Wen-Lin, He Li, Liu Xi-Hua, Wang Yu-Mei, Liu Jian-Qing
机构信息
Department of Ophthalmology, Shenzhen Children's Hospital, Shenzhen 518026, Guangdong Province, China.
出版信息
Int J Ophthalmol. 2011;4(6):631-3. doi: 10.3980/j.issn.2222-3959.2011.06.11. Epub 2011 Dec 18.
AIM
To analyze the incidence and risk factors for retinopathy of prematurity (ROP).
METHODS
A retrospective analysis was conducted on 568 premature infants from September 2005 to December 2010 with birth weight(BW) equal to or less than 2 500g or a gestational age(GA) at birth of 34 weeks or less. All of the members were examined by indirect binocular ophthalmoscopy.
RESULTS
ROP occurred with an incidence rate of 10.7% among 568 premature infants, and stages 3 and above ROP occurred with an incidence rate of 2.5%. This study showed the infants were more prone to develop ROP with short geststional age, low BW, long time of oxygen inhalation, and severe infants diseases. Twins had a significantly higher rate of ROP(18.3%) than singleton babies(9.8%), ROP were severer in twins than singleton babies.
CONCLUSION
Short GA, low BW, long time of oxygen inhalation, severe infants diseases, and non-singleton babies were the most significant risk factors associated with ROP.
目的
分析早产儿视网膜病变（ROP）的发病率及危险因素。
方法
对2005年9月至2010年12月出生体重（BW）小于或等于2500g或出生孕周（GA）小于或等于34周的568例早产儿进行回顾性分析。所有患儿均行间接检眼镜检查。
结果
568例早产儿中ROP发病率为10.7%，3期及以上ROP发病率为2.5%。本研究表明，孕周短、出生体重低、吸氧时间长及患有严重疾病的婴儿更容易发生ROP。双胞胎ROP发病率（18.3%）显著高于单胎婴儿（9.8%），且双胞胎ROP病情比单胎婴儿更严重。
结论
孕周短、出生体重低、吸氧时间长、患有严重疾病及非单胎婴儿是与ROP相关的最主要危险因素。
Zotero 插件