相似文献
1
Efficient synthesis of exo-N-carbamoyl nucleosides: application to the synthesis of phosphoramidate prodrugs.
Org Lett. 2012 May 18;14(10):2488-91. doi: 10.1021/ol300777p. Epub 2012 May 3.
2
A novel synthesis of antiviral nucleoside phosphoramidate and thiophosphoramidate prodrugs via nucleoside H-phosphonamidates.
Nucleosides Nucleotides Nucleic Acids. 2013;32(11):617-38. doi: 10.1080/15257770.2013.838262.
3
Diastereoselective synthesis of P-chirogenic phosphoramidate prodrugs of nucleoside analogues (ProTides) via copper catalysed reaction.
Chem Commun (Camb). 2015 May 11;51(38):8070-3. doi: 10.1039/c5cc00448a. Epub 2015 Apr 13.
4
Synthesis and biological evaluation of aryl phosphoramidate prodrugs of fosfoxacin and its derivatives.
Bioorg Chem. 2019 Aug;89:103012. doi: 10.1016/j.bioorg.2019.103012. Epub 2019 May 27.
5
Synthesis and antiviral evaluation of 2-amino-6-carbamoylpurine dioxolane nucleoside derivatives and their phosphoramidates prodrugs.
Bioorg Med Chem. 2014 Dec 1;22(23):6665-6671. doi: 10.1016/j.bmc.2014.10.003. Epub 2014 Oct 13.
6
Synthesis of 5'-methylene-phosphonate furanonucleoside prodrugs: application to D-2'-deoxy-2'-α-fluoro-2'-β-C-methyl nucleosides.
Org Lett. 2012 Sep 7;14(17):4426-9. doi: 10.1021/ol301937v. Epub 2012 Aug 23.
7
Model synthesis of nucleoside boranophosphoramidate with amino acid for prodrug purpose.
Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):675-8. doi: 10.1081/ncn-200060244.
8
Synthesis and anti-retroviral activity of O,O'-bis(3'-azido-2',3'-dideoxythymidin-5'-yl) phosphoramidate derivatives.
Nucleosides Nucleotides. 1999 Oct;18(10):2317-25. doi: 10.1080/07328319908044884.
9
A multifunctional catalyst that stereoselectively assembles prodrugs.
Science. 2017 Apr 28;356(6336):426-430. doi: 10.1126/science.aam7936.
10
Activation mechanisms of nucleoside phosphoramidate prodrugs.
J Med Chem. 2000 Nov 2;43(22):4319-27. doi: 10.1021/jm000302b.
引用本文的文献
1
Bromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases.
J Org Chem. 2015 Nov 6;80(21):10675-85. doi: 10.1021/acs.joc.5b01833. Epub 2015 Oct 28.
2
Nematode signaling molecules derived from multimodular assembly of primary metabolic building blocks.
Org Lett. 2015 Apr 3;17(7):1648-51. doi: 10.1021/acs.orglett.5b00329. Epub 2015 Mar 18.
3
Synthesis of nucleoside phosphate and phosphonate prodrugs.
Chem Rev. 2014 Sep 24;114(18):9154-218. doi: 10.1021/cr5002035. Epub 2014 Aug 21.
本文引用的文献
1
Discovery of PSI-353661, a Novel Purine Nucleotide Prodrug for the Treatment of HCV Infection.
ACS Med Chem Lett. 2010 Dec 17;2(2):130-5. doi: 10.1021/ml100209f. eCollection 2011 Feb 10.
2
Efficient synthesis of nucleoside aryloxy phosphoramidate prodrugs utilizing benzyloxycarbonyl protection.
Tetrahedron. 2011 Jul 29;67(30):5487-5493. doi: 10.1016/j.tet.2011.05.046.
3
Nucleotide prodrugs for HCV therapy.
Antivir Chem Chemother. 2011 Aug 23;22(1):23-49. doi: 10.3851/IMP1797.
4
Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides.
Bioorg Med Chem. 2011 Jan 1;19(1):229-42. doi: 10.1016/j.bmc.2010.11.029. Epub 2010 Dec 4.
5
Advances in nucleoside monophosphate prodrugs as anti-HCV agents.
Antivir Ther. 2010;15(7):935-50. doi: 10.3851/IMP1667.
6
Discovery of a β-d-2'-deoxy-2'-α-fluoro-2'-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus.
J Med Chem. 2010 Oct 14;53(19):7202-18. doi: 10.1021/jm100863x.
7
Phosphoramidate ProTides of 2'-C-methylguanosine as highly potent inhibitors of hepatitis C virus. Study of their in vitro and in vivo properties.
J Med Chem. 2010 Jul 8;53(13):4949-57. doi: 10.1021/jm1003792.
8
Tetramethylsuccinimide as a directing/protecting group in purine glycosylations.
Org Lett. 2010 Jan 1;12(1):120-2. doi: 10.1021/ol9025028.
9
Aryloxy phosphoramidate triesters: a technology for delivering monophosphorylated nucleosides and sugars into cells.
ChemMedChem. 2009 Nov;4(11):1779-91. doi: 10.1002/cmdc.200900289.
10
Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection.
J Med Chem. 2009 Sep 10;52(17):5394-407. doi: 10.1021/jm900447q.
Zotero 插件