John Hunter Hospital, Newcastle, Australia.
Heart Lung Circ. 2012 Aug;21(8):427-32. doi: 10.1016/j.hlc.2012.03.123. Epub 2012 May 2.
Cryoballoon ablation is a recently introduced technique to isolate the pulmonary veins in patients with atrial fibrillation (AF). It can potentially reduce procedural times and serious complications associated with radiofrequency ablation.
We present data for 200 consecutive patients who underwent cryoballoon ablation for symptomatic AF with a mean follow-up of 16 months.
Over 214 procedures that involved cryoballoon technique the mean procedure and fluoroscopy times fell to 130 and 30 min, respectively. 93.6% of pulmonary veins targeted were isolated with the cryoballoon only and 97.7% could be isolated with the addition of a radiofrequency ablation catheter. At one year 70% of patients in the paroxysmal AF group and 59% of patients in the persistent AF group were free from symptomatic recurrence. Three percent of patients experienced phrenic nerve palsy that persisted beyond the procedure. The major complication rate in this study was 0.9%.
This represents the earliest and largest experience with cryoballoon ablation for AF in Australia. The major complication rate was low with no pulmonary vein stenosis, atrio-oesophageal fistula, stroke or cardiac tamponade in this series. The majority of patients were free from symptomatic recurrence at two years follow up.
冷冻球囊消融术是一种最近引入的技术，用于隔离房颤（AF）患者的肺静脉。它有可能减少与射频消融相关的程序时间和严重并发症。
我们提供了 200 例连续接受冷冻球囊消融术治疗症状性房颤患者的数据，平均随访 16 个月。
在 214 次涉及冷冻球囊技术的手术中，平均手术和透视时间分别降至 130 分钟和 30 分钟。93.6%的目标肺静脉仅用冷冻球囊隔离，97.7%的肺静脉可以用射频消融导管隔离。在一年时，阵发性 AF 组中有 70%的患者和持续性 AF 组中有 59%的患者无症状复发。3%的患者出现膈神经麻痹，持续时间超过手术。本研究的主要并发症发生率为 0.9%。
这是澳大利亚最早和最大的冷冻球囊消融术治疗房颤的经验。在本系列中，主要并发症发生率低，无肺静脉狭窄、食管-心房瘘、中风或心脏压塞。大多数患者在两年随访时无症状复发。
