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[光复活作用在紫外线致角膜损伤中的作用]

[Role of photoreactivation in case of corneal damage from ultraviolet radiation].

作者信息

Lysak V F, Krasnovidov V S, Kidalov V N, Zelentsov I V, Marat O V

出版信息

Oftalmol Zh. 1990(4):242-5.

PMID:2255506
Abstract

Experimentally, the role of photoreactivation in appearance of ultraviolet lesions of corneal epithelium has been studied in white rats. The lesions were induced by ultraviolet radiation, 0.28 mcm wavelength, and intensive (20000 lx) light of a xenon lamp with light filters was used as a reactivating light. The damaging dose as a reactivating light. The damaging dose of ultraviolet radiation by photokeratitis criterion was 11 +/- 2.4 mJ.cm-2. Simultaneous illumination of the animal eye by the damaging ultraviolet light and reactivating radiation exceeded a damaging threshold to 18 +/- 4.0 mJ.cm-2. The results obtained have convincingly shown, that photoreactivation, as a phenomenon, manifested itself in the corneal epithelium and was detected by biomicroscopy of the eye with epithelium staining by a 1% fluorescein solution.

摘要

在实验中,已对白鼠角膜上皮紫外线损伤出现过程中光复活作用的角色进行了研究。损伤由波长0.28微米的紫外线辐射诱导产生,并用带有滤光片的氙灯发出的强光(20000勒克斯)作为复活光。以光性角膜炎标准衡量,紫外线辐射的损伤剂量为11±2.4毫焦·平方厘米-2。损伤性紫外线光和复活辐射同时照射动物眼睛时,超过损伤阈值至18±4.0毫焦·平方厘米-2。所获结果令人信服地表明,光复活作为一种现象在角膜上皮中表现出来,并且通过用1%荧光素溶液对上皮进行染色的眼部生物显微镜检查得以检测。

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