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[用纤连蛋白治疗溃疡性角膜病变的疗效]

[The efficiency of treating ulcerative corneal lesions with fibro nectin].

作者信息

Adamova N A, Gorgiladze T U, Artemov A V

出版信息

Oftalmol Zh. 1990(4):245-8.

PMID:2255507
Abstract

The paper analyses results after experimental studies of effectiveness of medical forms of fibronectin used in a form of eye drops for treatment of infectious keratitis on a model of bacterial corneal ulcer in 30 rabbits (60 eyes). The results obtained speak about a pronounced stimulating action of fibronectin on reparative processes: almost a twice quicker epithelialization of corneal defects (by 46.8%) and a quicker reverse development of inflammatory signs as compared with the control group of animals. Results of experimental studies allow to recommend fibronectin for treatment of patients with infectious keratitis, bacterial ulcers of the cornea.

摘要

本文分析了以眼药水形式使用的医学形式的纤连蛋白对30只兔子(60只眼睛)的细菌性角膜溃疡模型治疗感染性角膜炎有效性的实验研究结果。所获得的结果表明纤连蛋白对修复过程具有显著的刺激作用:与动物对照组相比,角膜缺损上皮化几乎快两倍(快46.8%),炎症体征的逆向发展也更快。实验研究结果允许推荐纤连蛋白用于治疗感染性角膜炎、细菌性角膜溃疡患者。

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