Laboratory of Mesoscopic Chemistry and Department of Polymer Science & Engineering, College of Chemistry & Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China.
Chem Asian J. 2012 Aug;7(8):1875-80. doi: 10.1002/asia.201200155. Epub 2012 May 3.
The non-membrane-closing formation of polymer vesicles was demonstrated by the self-assembly of an amphiphilic hydrogen-bonded interpolymer complex of HPC and PAA. A dynamic-formation process that involved a nucleation and growth pathway was observed experimentally that was different from the theoretical predictions of both the membrane-closing model and the nucleation and growth model. A series of intermediate states between the solid spheres and vesicles were visually captured by the addition of an inorganic salt followed by dilution.
非膜封闭聚合物囊泡的形成是由 HPC 和 PAA 的两亲氢键互聚物自组装来证明的。实验观察到的动态形成过程与膜封闭模型和成核生长模型的理论预测都不同，涉及成核和生长途径。通过添加无机盐再稀释的方法，我们可以直观地捕捉到从固体球到囊泡的一系列中间状态。
