Ernst Arneborg
HNO-Klinik, Unfallkrankenhaus Berlin, Germany.
GMS Curr Top Otorhinolaryngol Head Neck Surg. 2011;10:Doc05. doi: 10.3205/cto000078. Epub 2012 Apr 26.
Vestibular diagnostics and therapy ist the mirror of technological, scientific and socio-economics trends as are other fields of clinical medicine. These trends have led to a substantial diversification of the field of neurotology.The improvements in diagnostics have been characterized by the introduction of new receptor testing tools (e.g., VEMPs), progress in imaging (e.g., the endolymphatic hydrops) and in the description of central-vestibular neuroplasticity. The etiopathology of vestibular disorders has been updated by geneticists (e.g., the description of the COCH gene mutations), the detection of structural abnormalities (e.g., dehiscence syndromes) and related disorders (e.g. migraine-associated vertigo). The therapeutic options were extended by re-evaluation of techniques known a long time ago (e.g., saccus exposure), the development of new approaches (e.g., dehiscence repair) and the introduction of new drug therapy concepts (e.g., local drug delivery). Implantable, neuroprosthetic solutions have not yet reached experimental safety and validity and are still far away. However, externally worn neuroprosthetic solution were introduced in the rehab of vestibular disorders (e.g., VertiGuard system).These and related trends point into a medical future which is characterized by presbyvertigo as classical sign of the demographic changes ahead, by shortage of financial resources and a medico-legally over-regulated, even hostile environment for physicians in clinical medicine.
前庭诊断与治疗如同临床医学的其他领域一样,是技术、科学和社会经济趋势的反映。这些趋势导致了神经耳科学领域的大幅多样化。诊断方面的进展表现为新受体检测工具(如视频眼震图)的引入、成像技术的进步(如内淋巴积水)以及中枢前庭神经可塑性描述的进展。前庭疾病的病因病理学已因遗传学家(如COCH基因突变的描述)、结构异常(如裂隙综合征)及相关疾病(如偏头痛相关性眩晕)的发现而得到更新。治疗选择通过对早就为人所知的技术(如囊暴露)的重新评估、新方法(如裂隙修复)的开发以及新药物治疗概念(如局部药物递送)的引入而得以扩展。可植入的神经假体解决方案尚未达到实验安全性和有效性,仍有很大差距。然而,外部佩戴的神经假体解决方案已被引入前庭疾病的康复治疗(如VertiGuard系统)。这些及相关趋势指向一个医学未来,其特征是老年眩晕作为即将到来的人口结构变化的典型标志、财政资源短缺以及临床医学领域对医生而言医疗法律监管过度甚至充满敌意的环境。