Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester MN 55905, USA.
Clin Biochem. 2012 Jul;45(10-11):842-4. doi: 10.1016/j.clinbiochem.2012.04.014. Epub 2012 Apr 26.
In an attempt to reduce false positive results and improve turnaround time, we investigated the BD Rapid Serum Tube as an alternate sample type to lithium heparin plasma for Roche Troponin T analysis on the Roche Cobas e411 analyzer.
BD Plasma Separator Tubes (PST) and Rapid Serum Tubes (RST) were collected in tandem from Emergency Department patients who had clinical orders for Troponin T over a 1 month period.
RST and PST samples yielded analytically and clinically concordant Troponin T results on the Roche Cobas e411. Rare false positive results in lithium heparin samples were not observed with rapid clot serum tubes.
RST samples are appropriate for stat Troponin T analysis, and appear to reduce the incidence of rare false positive Troponin T results obtained with lithium heparin samples.
为了减少假阳性结果并缩短周转时间,我们研究了 BD Rapid Serum Tube(快速血清管)作为替代样本类型,用于罗氏 Cobas e411 分析仪上罗氏 Troponin T 分析,替代肝素锂血浆。
在一个月的时间内,从急诊科有肌钙蛋白 T 医嘱的患者中连续采集 BD Plasma Separator Tubes(PST,血浆分离管)和 Rapid Serum Tubes(RST,快速血清管)。
RST 和 PST 样本在罗氏 Cobas e411 上产生了分析和临床一致的肌钙蛋白 T 结果。快速凝固血清管未观察到肝素锂样本中罕见的假阳性结果。
RST 样本适用于即刻肌钙蛋白 T 分析,似乎减少了肝素锂样本中罕见的假阳性肌钙蛋白 T 结果的发生率。