评价植物提取物对淋巴丝虫病传播媒介——致倦库蚊的毒性。
Evaluation of toxicity of plant extracts against vector of lymphatic filariasis, Culex quinquefasciatus.
机构信息
National Institute of Malaria Research, ICMR, IDVC Field Unit, Chennai, India.
出版信息
Indian J Med Res. 2012 Mar;135(3):397-400.
BACKGROUND & OBJECTIVES: Conventional insecticides are generally used as larvicides to control Culex quinquefasciatus, vector of lymphatic filariasis. This study was undertaken to evaluate the larvicidal activity of some potential larvicidal plants leaf extracts against Cx. quinquefasciatus larvae.
METHODS
The toxic effects of petroleum ether leaf extracts of plants viz., Argemone mexicana (Mexican prickly poppy), Clausena dentata (Dentate), Cipadessa baccifera (Rana bili), Dodonaea angustifolia (Hop bush) and Melia dubia (Pride of India) were evaluated under laboratory conditions in individual and in combination against 3 rd - 4 th instar larvae of Cx. quinquefasciatus.
RESULTS
The results indicated that among the selected plants, A. mexicana showed maximum larvicidal activity with an LC 50 value of 48.89 ppm. Its toxicity was enhanced when the extract was mixed (1:1) with that of C. dentata as the LC 50 value became 28.60 ppm indicating synergistic action of A. mexicana.
INTERPRETATION & CONCLUSIONS: Our results showed high larvicidal potential in A. mexicana leaf extract, and it also showed additive effect when mixed with C. dentata extract.
背景与目的
常规杀虫剂通常被用作杀幼虫剂来控制淋巴丝虫病的传播媒介——致倦库蚊。本研究旨在评估一些潜在杀幼虫植物叶提取物对致倦库蚊幼虫的杀幼虫活性。
方法
在实验室条件下，单独和联合使用植物的石油醚叶提取物（墨西哥刺罂粟、齿叶黄皮、长序榆、Hop bush 和印度紫檀）对 3 龄至 4 龄致倦库蚊幼虫进行毒性评估。
结果
结果表明，在所选择的植物中，墨西哥刺罂粟表现出最大的杀幼虫活性，LC50 值为 48.89 ppm。当提取物与黄皮（1:1）混合时，其毒性增强，LC50 值变为 28.60 ppm，表明墨西哥刺罂粟具有协同作用。
解释与结论
我们的结果表明，墨西哥刺罂粟叶提取物具有很高的杀幼虫潜力，与黄皮提取物混合使用时表现出相加作用。
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