Islam M N, Hossain M A, Khaleque M A, Karim M R, Khan M R, Mia A H, Ali M S
Department of Neonatology, Mymensingh Medical College, Mymensingh, Bangladesh.
Mymensingh Med J. 2012 Apr;21(2):372-6.
Many countries in the world have reported human infections by chikungunya virus (CHIKV) a mosquito-borne togavirus belonging to the genus alpha virus. After half a century of focal out breaks of acute febrile poly arthralgia, the disease had spread unexpectedly in the past decade with large outbreaks in Africa around the Indian Ocean and in Bangladesh. In Asia, CHIKV is thought to be transmitted by the same mosquito as dengue, Aedes aegypti and Aedes albopictus. Due to similarities in clinical presentation with dengue, limited awareness and a lack of laboratory diagnostic facilities, CHIKV is probably often under diagnosed or misdiagnosed as dengue. Treatment is supportive. The prognosis is generally good although some patients experience chronic arthritis. There is no vaccine or antiviral therapy against CHIKV. Early identification of disease and control of vector will prevent the spread of disease.
世界上许多国家都报告了人类感染基孔肯雅病毒(CHIKV)的情况,该病毒是一种由蚊子传播的披膜病毒,属于甲病毒属。在经历了半个世纪的急性发热性多关节痛局部爆发后,该病在过去十年中意外蔓延,在印度洋周边非洲地区和孟加拉国出现了大规模疫情。在亚洲,基孔肯雅病毒被认为是通过与登革热相同的蚊子传播的,即埃及伊蚊和白纹伊蚊。由于临床表现与登革热相似、认识有限以及缺乏实验室诊断设施,基孔肯雅病毒很可能经常被漏诊或误诊为登革热。治疗以支持性治疗为主。尽管一些患者会出现慢性关节炎,但总体预后良好。目前尚无针对基孔肯雅病毒的疫苗或抗病毒疗法。早期识别疾病并控制病媒将预防疾病传播。