UNIFESP EPM, Allergy and Immunology.
J Trop Pediatr. 2012 Dec;58(6):501-4. doi: 10.1093/tropej/fms016. Epub 2012 May 4.
The objective of this study was to identify risk factors for wheezing disorders in the first year of life in infants living in São Paulo (SP), Brazil, applying the standardized protocol of the Estudio Internacional de sibilancia en lactentes-Phase 1. A total of 1014 parents or caregivers of infants, who attended for routine evaluation and immunization in public health centers were interviewed in Southern SP city. Risk factors significantly associated with recurrent wheezing were: history of previous pneumonia, daycare attendance, consumption of processed food, presence of a cat at home, more than five upper respiratory infection (URI) episodes and the first URI before the age of sixth month. Most of these risk factors for wheezing can be avoided or controlled. Prospective studies on wheezing, especially in children with a severe presentation, are needed to analyze the impact of these risk factors and the effect of preventive actions.
本研究旨在通过应用国际婴幼儿喘息研究-第 1 阶段的标准化方案，确定巴西圣保罗（SP）地区婴儿生命第一年喘息障碍的危险因素。共对 SP 市南部 1014 名接受常规评估和免疫接种的婴儿的父母或照顾者进行了访谈。与反复喘息显著相关的危险因素包括：既往肺炎史、日托、食用加工食品、家中有猫、上呼吸道感染（URI）发作超过 5 次以及 6 月龄前首次 URI。这些喘息的危险因素大多可以避免或控制。需要对喘息进行前瞻性研究，尤其是对严重表现的儿童进行研究，以分析这些危险因素的影响以及预防措施的效果。
