University of Wisconsin-Madison School of Medicine and Public Health, Wisconsin, USA.
J Speech Lang Hear Res. 2012 Dec;55(6):1850-61. doi: 10.1044/1092-4388(2012/11-0240). Epub 2012 May 4.
To model tension asymmetry caused by superior laryngeal nerve paralysis (SLNP) in excised larynges and apply perturbation, nonlinear dynamic, and aerodynamic analyses.
SLNP was modeled in 8 excised larynges using sutures and weights to mimic cricothyroid (CT) muscle function. Weights were removed from one side to create tension asymmetry, mimicking unilateral SLNP. Two sets of weights were used, 1 light and 1 heavy. Five conditions were evaluated: (a) no tension, (b) symmetrical light tension, (c) asymmetrical light tension, (d) symmetrical heavy tension, and (e) asymmetrical heavy tension.
Perturbation parameters were not significantly different across conditions: percent jitter, χ(2)(4) = 3.70, p = .451; percent shimmer, F(4) = 0.95, p = .321. In addition, many measurements were invalid (error values >10). Second-order entropy was significantly different across conditions, F(4) = 5.432, p = .002, whereas correlation dimension was not, F(4) = 0.99, p = .428. Validity of these nonlinear dynamic parameters was demonstrated by low standard deviations. Phonation threshold pressure, χ (2)(4) = 22.50, p < .001, and power, χ (2)(4) = 9.50, p = .05, differed significantly across conditions, whereas phonation threshold flow did not, χ (2)(4) = 4.08, p = .396.
Nonlinear dynamic analysis differentiated between symmetrical and asymmetrical tension conditions, whereas traditional perturbation analysis was less useful in characterizing type 2 or 3 vocal signals. Supplementing acoustic with aerodynamic parameters may help distinguish among laryngeal disorders of neuromuscular origin.
在切除的喉中模拟因喉上神经麻痹（SLNP）引起的张力不对称，并应用摄动、非线性动力学和空气动力学分析。
使用缝线和重物在 8 个切除的喉中模拟环甲肌（CT）的功能，以模拟单侧 SLNP 来建立张力不对称。一侧去除重物，造成张力不对称，模拟单侧 SLNP。使用两组重量，一组轻，一组重。评估了 5 种情况：（a）无张力；（b）对称轻张力；（c）不对称轻张力；（d）对称重张力；（e）不对称重张力。
摄动参数在不同条件下没有显著差异：（a）%颤噪， χ(2)(4) = 3.70，p =.451；（b）%齿状，F(4) = 0.95，p =.321。此外，许多测量值无效（误差值>10）。二阶熵在不同条件下有显著差异，F(4) = 5.432，p =.002，而相关维数则没有，F(4) = 0.99，p =.428。这些非线性动力学参数的有效性通过低标准差来证明。声门闭合力， χ (2)(4) = 22.50，p <.001，功率， χ (2)(4) = 9.50，p =.05，在不同条件下有显著差异，而声门闭合力流则没有， χ (2)(4) = 4.08，p =.396。
非线性动力学分析可以区分对称和不对称的张力条件，而传统的摄动分析在描述 2 型或 3 型声信号方面作用较小。声学与空气动力学参数的补充可能有助于区分神经肌肉来源的喉疾病。
