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喉模型的发声阈功率。

Phonation threshold power in ex vivo laryngeal models.

机构信息

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53706, USA.

出版信息

J Voice. 2011 Sep;25(5):519-25. doi: 10.1016/j.jvoice.2010.04.001. Epub 2010 Sep 2.

DOI:10.1016/j.jvoice.2010.04.001
PMID:20817475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3182454/
Abstract

This study hypothesized that phonation threshold power is measureable and sensitive to changes in the biomechanical properties of the vocal folds. Phonation threshold power was measured in three sample populations of 10 excised canine larynges treated with variable posterior glottal gap, variable bilateral vocal fold elongation, and variable vocal fold lesioning. Posterior glottal gap varied from 0 to 4mm in 0.5 mm intervals. Bilateral vocal fold elongation varied from 0% to 20% in 5% intervals. Vocal fold lesion treatments included unilateral and bilateral vocal fold lesion groups. Each treatment was investigated independently in a sample population of 10 excised canine larynges. Linear regression analysis indicated that phonation threshold power was sensitive to posterior glottal gap (R2=0.298, P<0.001) and weakly to vocal fold elongation (R2=0.052, P=0.003). A one-way repeated measures analysis of variance indicated that phonation threshold power was sensitive to the presence of lesions (P<0.001). Theoretical and experimental evidence presented here suggests that phonation threshold power could be used as a broad screening parameter sensitive to certain changes in the biomechanical properties of the larynx. It has not yet been measured in humans, but because it has the potential to represent the airflow-tissue energy transfer more completely than the phonation threshold pressure or flow alone, it may be a more useful parameter than these and could be used to indicate that laryngeal health is likely abnormal.

摘要

本研究假设发声阈能可测量,并对声带的生物力学特性变化敏感。发声阈能在三个样本群体中进行了测量,每个样本群体包含 10 个切除的犬喉,接受不同的后声门隙、双侧声带延长和声带病变处理。后声门隙以 0.5mm 的间隔从 0 到 4mm 变化。双侧声带延长以 5%的间隔从 0%变化到 20%。声带病变处理包括单侧和双侧声带病变组。每个处理在 10 个切除的犬喉样本群体中独立进行研究。线性回归分析表明,发声阈能对后声门隙敏感(R2=0.298,P<0.001),对声带延长较弱敏感(R2=0.052,P=0.003)。单向重复测量方差分析表明,发声阈能对病变的存在敏感(P<0.001)。本文提出的理论和实验证据表明,发声阈能可用作对喉生物力学特性某些变化敏感的广泛筛选参数。它尚未在人类中进行测量,但由于它有可能比单独的发声阈压或流量更完整地代表气流-组织能量传递,因此它可能比这些参数更有用,并可用于指示喉健康可能异常。

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本文引用的文献

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Effect of dehydration on phonation threshold flow in excised canine larynges.脱水对离体犬喉发声阈流量的影响。
Ann Otol Rhinol Laryngol. 2009 Feb;118(2):154-9. doi: 10.1177/000348940911800212.
2
Phonation threshold flow measurements in normal and pathological phonation.正常和病理性发声中的发声阈值流量测量
Laryngoscope. 2009 Apr;119(4):811-5. doi: 10.1002/lary.20165.
3
Phonation threshold flow in elongated excised larynges.离体延长喉的发声阈流量
Ann Otol Rhinol Laryngol. 2008 Jul;117(7):548-53. doi: 10.1177/000348940811700714.
4
Comparing phonation threshold flow and pressure by abducting excised larynges.通过外展离体喉来比较发声阈值流量和压力。
Laryngoscope. 2007 Sep;117(9):1695-9. doi: 10.1097/MLG.0b013e3180959e38.
5
On the relation between the phonation threshold lung pressure and the oscillation frequency of the vocal folds.关于发声阈值肺压与声带振荡频率之间的关系。
J Acoust Soc Am. 2007 Jun;121(6):3280-3. doi: 10.1121/1.2722210.
6
The minimum glottal airflow to initiate vocal fold oscillation.启动声带振动的最小声门气流。
J Acoust Soc Am. 2007 May;121(5 Pt1):2873-81. doi: 10.1121/1.2710961.
7
Dependence of phonation threshold pressure on vocal tract acoustics and vocal fold tissue mechanics.发声阈压力对声道声学和声带组织力学的依赖性。
J Acoust Soc Am. 2006 Apr;119(4):2351-62. doi: 10.1121/1.2173516.
8
Prevention of vocal fold scarring by topical injection of hepatocyte growth factor in a rabbit model.在兔模型中通过局部注射肝细胞生长因子预防声带瘢痕形成
Laryngoscope. 2004 Mar;114(3):548-56. doi: 10.1097/00005537-200403000-00030.
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Aerodynamic measurements of patients with Parkinson's disease.帕金森病患者的空气动力学测量。
J Voice. 1999 Dec;13(4):583-91. doi: 10.1016/s0892-1997(99)80012-5.
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The effects of age and gender on laryngeal aerodynamics.年龄和性别对喉部空气动力学的影响。
Int J Lang Commun Disord. 1998 Apr-Jun;33(2):221-38. doi: 10.1080/136828298247884.