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Invest Ophthalmol Vis Sci. 2012 May 4;53(5):2476-81. doi: 10.1167/iovs.12-9483h.
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Involvement of the Bcl2 gene family in the signaling and control of retinal ganglion cell death.Bcl2基因家族在视网膜神经节细胞死亡的信号传导与调控中的作用。
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Functional significance of commonly regulated genes in mechanically and chemically induced retinal ganglion cell death in rat eyes.大鼠眼中机械性和化学性诱导视网膜神经节细胞死亡中共同调控基因的功能意义。
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Crystallin β-b2 promotes retinal ganglion cell protection in experimental autoimmune uveoretinitis.晶状体β - b2在实验性自身免疫性葡萄膜视网膜炎中促进视网膜神经节细胞保护。
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Pigment Epithelium-Derived Factor Binding to VEGFR-1 (Flt-1) Increases the Survival of Retinal Neurons.色素上皮衍生因子与 VEGFR-1（Flt-1）结合可增加视网膜神经元的存活率。
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Sensitivity and specificity of the uniform field electroretinogram in glaucoma detection in comparison to the pattern electroretinogram.均场视网膜电图在青光眼检测中的敏感性和特异性与图形视网膜电图的比较。
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Molecular Mechanisms of Glaucoma Pathogenesis with Implications to Caveolin Adaptor Protein and Caveolin-Shp2 Axis.青光眼发病机制的分子机制及其对窖蛋白衔接蛋白和窖蛋白-Shp2 轴的影响。
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本文引用的文献

1
JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death.JNK2 和 JNK3 是轴突损伤诱导的视网膜神经节细胞死亡的主要调节因子。
Neurobiol Dis. 2012 May;46(2):393-401. doi: 10.1016/j.nbd.2012.02.003. Epub 2012 Feb 14.
2
BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina.BBC3（PUMA）调节视网膜发育性细胞凋亡，但不调节轴突损伤诱导的细胞死亡。
Mol Neurodegener. 2011 Jul 15;6:50. doi: 10.1186/1750-1326-6-50.
3
Bcl-x(L) retrotranslocates Bax from the mitochondria into the cytosol.Bcl-x(L) 将 Bax 从线粒体逆向转位到细胞质中。
Cell. 2011 Apr 1;145(1):104-16. doi: 10.1016/j.cell.2011.02.034.
4
Similarities and differences between primary and secondary degeneration of the optic nerve and the effect of minocycline.视神经原发性和继发性变性的异同及米诺环素的作用。
Graefes Arch Clin Exp Ophthalmol. 2011 Jun;249(6):849-57. doi: 10.1007/s00417-010-1608-2. Epub 2011 Jan 13.
5
Retinal ganglion cell loss in a rat ocular hypertension model is sectorial and involves early optic nerve axon loss.大鼠眼高压模型中的视网膜神经节细胞丢失呈扇区性，且涉及早期视神经轴突丢失。
Invest Ophthalmol Vis Sci. 2011 Jan 21;52(1):434-41. doi: 10.1167/iovs.10-5856. Print 2011 Jan.
6
Microglia in the healthy and degenerating retina: insights from novel mouse models.健康和退化的视网膜中的小胶质细胞：来自新型小鼠模型的见解。
Immunobiology. 2010 Sep-Oct;215(9-10):685-91. doi: 10.1016/j.imbio.2010.05.010. Epub 2010 Jun 4.
7
Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis.组蛋白 H4 去乙酰化在神经元凋亡过程中的早期基因沉默中起着关键作用。
BMC Neurosci. 2010 May 26;11:62. doi: 10.1186/1471-2202-11-62.
8
A single nucleotide polymorphism in the Bax gene promoter affects transcription and influences retinal ganglion cell death.Bax 基因启动子中的单核苷酸多态性影响转录并影响视网膜神经节细胞死亡。
ASN Neuro. 2010 Mar 31;2(2):e00032. doi: 10.1042/AN20100003.
9
Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism.视网膜神经元在体内的兴奋性毒性死亡通过非细胞自主机制发生。
J Neurosci. 2009 Apr 29;29(17):5536-45. doi: 10.1523/JNEUROSCI.0831-09.2009.
10
Spatial summation properties for magnocellular and parvocellular pathways in glaucoma.青光眼大细胞和小细胞通路的空间总和特性
Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1221-6. doi: 10.1167/iovs.08-2517. Epub 2008 Oct 20.

The cell and molecular biology of glaucoma: mechanisms of retinal ganglion cell death.

作者信息

Nickells Robert W

机构信息

Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA.

出版信息

Invest Ophthalmol Vis Sci. 2012 May 4;53(5):2476-81. doi: 10.1167/iovs.12-9483h.

DOI:10.1167/iovs.12-9483h
PMID:22562845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3990459/
Abstract
摘要