Iarosh A A, Prokopiv M M, Zhovnir I K, Kanevskaia S A
Vrach Delo. 1990 Aug(8):70-2.
The authors examined the dynamics of IgA, IgM, IgG in the blood of 100 patients with multiple sclerosis. Of them 50 patients received complex treatment in combination with prednisolone. Comparison of indices of concentration of serum immunoglobulins revealed a distinct reduction of their level of all classes in patients with multiple sclerosis, especially in those receiving prednisolone. Prednisolone produced an unfavourable effect on the course of the demyelinating process in patients with multiple sclerosis.
作者研究了100例多发性硬化症患者血液中IgA、IgM、IgG的动态变化。其中50例患者接受了泼尼松龙联合综合治疗。血清免疫球蛋白浓度指标的比较显示，多发性硬化症患者所有类别的免疫球蛋白水平均明显降低，尤其是接受泼尼松龙治疗的患者。泼尼松龙对多发性硬化症患者的脱髓鞘过程产生了不利影响。
