Department of Medical Physics, University of Applied Sciences TFH Berlin, Berlin, Germany.
Int J Cosmet Sci. 2012 Aug;34(4):285-90. doi: 10.1111/j.1468-2494.2012.00718.x. Epub 2012 May 5.
A scale of skin treatments is analysed, which bases on the detection of UV-generated free radicals in pig skin. Physiological and anatomical similarities between man and pig made this animal a good model for man in many research areas. The determination of the Radical Status (free radical response) offers the possibility to see in an early stage the effect of exterior and interior influences. The detection of the skin's response after a normalized radical generation by defined UV dose combined with the application of external and internal influences enables a comprehensive and easy classification of skin products and therapies. The effect of substances, especially, applied topically on the skin, like it is usual in cosmetics and pharmacy, can be classified. The relevance of the RSF method is demonstrated with the application of numerous different treatments on the skin.
分析了一种皮肤处理量表,该量表基于猪皮中紫外线产生的自由基的检测。人与猪在生理和解剖学上的相似性使这种动物成为许多研究领域中人类的良好模型。自由基状态(自由基反应)的确定提供了早期观察外部和内部影响的可能性。通过定义的紫外线剂量产生标准化自由基后检测皮肤的反应,并结合外部和内部影响的应用,使皮肤产品和疗法的综合和易于分类成为可能。可以对物质进行分类,特别是像在化妆品和制药中那样局部应用于皮肤的物质。通过在皮肤上应用许多不同的治疗方法来证明 RSF 方法的相关性。