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面神经肿瘤的治疗结果:观察、CyberKnife 和手术治疗的对比结果。

Management outcomes of facial nerve tumors: comparative outcomes with observation, CyberKnife, and surgical management.

机构信息

Department of Otolaryngology, University of Miami, Miami, Florida 33136, USA.

出版信息

Otolaryngol Head Neck Surg. 2012 Sep;147(3):525-30. doi: 10.1177/0194599812446686. Epub 2012 May 7.

DOI:10.1177/0194599812446686
PMID:22565049
Abstract

OBJECTIVES

Primary facial nerve tumors (FNTs) present in varying ways. In this study, the authors present their institutional experience with the management of facial nerve tumors, including their recommendations for available therapies such as observation, microsurgical decompression or removal, and stereotactic radiation. They emphasize the auditory and facial nerve function outcomes.

STUDY DESIGN

Retrospective case review.

SETTING

Tertiary referral center.

SUBJECTS AND METHODS

Retrospective review of all cases of FNT seen at the authors' tertiary care academic medical center over a 10-year period (2002-2011). The clinical presentation, treatment modality, and outcome parameters of cochlear and facial nerve function were assessed.

RESULTS

Twelve patients were identified. House-Brackmann grades on presentation were 4 grade I, 2 grade II, 2 grade III, 1 grade IV, and 3 grade V, with 2 grade V patients declining to grade VI shortly after presentation. Seven patients presented with serviceable hearing and 4 with nonserviceable hearing. Treatment options/arms included observation with serial clinicoradiological review (2 cases), stereotactic radiation with the CyberKnife (3 cases), wide fallopian canal decompression (3 cases), microsurgical excision and repair (3 cases), and biopsy followed by observation (1 case). At the end of the review period, facial nerve function was stable in 8 patients, improved in 3, and declined in 1, and none had documented worsening of hearing based on American Academy of Otolaryngology--Head and Neck Surgery Foundation classification.

CONCLUSIONS

Management of FNT is largely based on the clinicoradiological picture. Each treatment arm is different, but overall auditory and facial function can be maintained.

摘要

目的

原发性面神经肿瘤(FNT)的表现形式多种多样。本研究作者介绍了他们在面神经肿瘤治疗方面的机构经验,包括他们对现有治疗方法的建议,如观察、显微外科减压或切除以及立体定向放射治疗。他们强调了听觉和面神经功能的结果。

研究设计

回顾性病例回顾。

设置

三级转诊中心。

受试者和方法

回顾性分析作者所在三级医疗学术中心 10 年间(2002-2011 年)所有面神经肿瘤病例。评估了听神经和面神经功能的临床表现、治疗方式和结局参数。

结果

共确定了 12 例患者。就诊时 House-Brackmann 分级为 4 级 I 型 2 例、2 级 II 型 2 例、2 级 III 型 1 例、1 级 IV 型和 3 级 V 型,其中 2 例 3 级 V 型患者在就诊后不久降为 6 级。7 例患者表现为可利用听力,4 例患者表现为不可利用听力。治疗方案/分支包括:连续临床放射学复查观察(2 例)、CyberKnife 立体定向放射治疗(3 例)、宽面神经管减压(3 例)、显微切除和修复(3 例)、活检后观察(1 例)。在回顾期末,8 例患者面神经功能稳定,3 例患者改善,1 例患者恶化,根据美国耳鼻喉科学会-头颈外科学会基金会分类,无听力恶化的记录。

结论

面神经肿瘤的治疗主要基于临床影像学表现。每个治疗分支都不同,但总体上可以维持听觉和面神经功能。

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