Suppr超能文献

[二亚硝基铁与半胱氨酸的复合物可阻断大鼠实验性子宫内膜异位症的发展]

[The dinitrosyl-iron complexes with cysteine block the development of experimental endometriosis in rats].

作者信息

Burgova E N, Tkachev N A, Vanin A F

出版信息

Biofizika. 2012 Jan-Feb;57(1):105-9.

Abstract

It has been shown that the administration of 0,5 ml of 5 mM aqueous solution of dinitrosyl-iron complexes (DNIC) with cysteine alleviated the development of experimental endometriosis in rats induced by surgical way: the size of endometriomes decreased 1.85 times when the DNIC was added every day during 10 days. The effect was suggested to be due to cytotoxic action of NO molecules and nitrosonium ions (NO+) released from rapidly decomposed DNIC in animal organism on endometriome tissues.

摘要

已经表明,给大鼠腹腔注射0.5毫升5毫摩尔/升的二亚硝基铁配合物(DNIC)与半胱氨酸的水溶液,可缓解手术诱导的大鼠实验性子宫内膜异位症的发展:在10天内每天添加DNIC时,子宫内膜瘤的大小减小了1.85倍。据推测,这种作用是由于动物体内快速分解的DNIC释放的NO分子和亚硝基离子(NO+)对子宫内膜瘤组织的细胞毒性作用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验