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帕金森病与衰老的关系。年轻帕金森病患者与健康老年患者步态模式的比较。

The relation between Parkinson's disease and ageing. Comparison of the gait patterns of young Parkinson's disease subjects with healthy elderly subjects.

机构信息

IRCCS San Raffaele, Rome, Italy.

出版信息

Eur J Phys Rehabil Med. 2013 Apr;49(2):161-7. Epub 2012 May 8.

PMID:22569487
Abstract

BACKGROUND

The gait of healthy elderly and of subjects with Parkinson's disease (PD) displays some common features, suggesting that PD may be a model of ageing.

AIM

The aim of the study was to quantify highlight the differences and similarities between the gait patterns of young PD and healthy elderly, to uncover if PD could be assumed as a model of ageing.

DESIGN

An optoelectronic system was used for 3D gait analysis evaluation.

POPULATION AND METHODS

We compared the gait parameters of 15 young PD (YPD) with the gait of 32 healthy elderly subjects (ES) and 21 healthy subjects age-matched with the PD subjects. RESULTS. Common features between YPD and ES were majorly found in the parameters that reflect the presence of an unstable, uncertain gait, and of corrective strategies employed to reduce instability. On the other side, typical features were present in the gait patterns of PD subjects. CONCLUSION. Our study helped identifying some typical characteristics of the onset disease, and to unravel the symptoms of ageing from those of PD by comparing young PD subjects to elderly healthy subjects.

CLINICAL REHABILITATION IMPACT

This allows a deeper understanding of the mechanisms underlying the gait in ageing and PD.

摘要

背景

健康老年人和帕金森病(PD)患者的步态存在一些共同特征,这表明 PD 可能是衰老的模型。

目的

本研究旨在量化和强调年轻 PD 患者和健康老年人步态模式之间的差异和相似之处,以揭示 PD 是否可以被假设为衰老的模型。

设计

使用光电系统进行 3D 步态分析评估。

人群和方法

我们比较了 15 名年轻 PD(YPD)患者的步态参数与 32 名健康老年人(ES)的步态以及与 PD 患者年龄匹配的 21 名健康受试者的步态参数。结果。YPD 和 ES 之间的共同特征主要存在于反映不稳定、不确定步态的参数中,以及用于减少不稳定性的纠正策略中。另一方面,PD 患者的步态模式存在典型特征。结论。我们的研究有助于识别疾病发作的一些典型特征,并通过将年轻 PD 患者与健康老年人进行比较,从 PD 症状中揭示衰老症状。

临床康复影响

这可以更深入地了解衰老和 PD 中步态的潜在机制。

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