Department of Biomorphological and Functional Science, Section of Anatomic Pathology, Federico II University, Naples, Italy.
Pathol Res Pract. 2012 Jun 15;208(6):372-5. doi: 10.1016/j.prp.2012.04.001. Epub 2012 May 7.
Glomus tumors are uncommon mesenchymal tumors whose cells closely resemble those of a normal glomus body, and are found most commonly in the hand. Recently, a symplastic form exhibiting marked nuclear atypia, in the absence of any other malignant features, has been described. To date, only 14 cases of symplastic glomus tumor have been reported in the literature; hence, very little information is available about its diagnosis, treatment, and biological behavior. The case reported here concerns a symplastic glomus tumor occurring in the right index finger of a 62-year-old woman. We reviewed the literature concerning previously reported cases, placing emphasis on the documented biological behavior, treatment, and demographic trend. Physicians must be aware of this morphological variation of glomus tumor to avoid the mistake of malignancy, which results in over-treatment of the patient.
血管球瘤是一种罕见的间叶性肿瘤，其细胞与正常血管球非常相似，最常见于手部。最近，已经描述了一种无其他恶性特征但具有明显核异型性的同形性形式。迄今为止，文献中仅报道了 14 例同形性血管球瘤病例；因此，关于其诊断、治疗和生物学行为的信息非常有限。本报告病例涉及一位 62 岁女性右手食指的同形性血管球瘤。我们复习了文献中以前报道的病例，重点关注已记录的生物学行为、治疗和人口统计学趋势。医生必须意识到血管球瘤的这种形态学变异，以避免恶性肿瘤的误诊，从而导致对患者的过度治疗。
