[Clinical course of recent insulin-dependent diabetes mellitus and possibilities of controlling it therapeutically].

Intensive insulin treatment in a recent stage of IDDM promotes metabolic compensation of the disease regardless which regime of conventional or unconventional treatment is used. In thus treated patients more frequently complete or partial metabolic remission is achieved. C-peptide in patients in remission is much higher than in other patients, and conversely there are fewer persons without residual B-cell secretion. The manifestation of diabetes has an impact also on the clinical course of the disease. Normoglycaemia with possible metabolic remission associated with easy insulin administration a flexible lifestyle have a favourable effect on the onset of the life-long disease and eliminate to a minimum factors which have a negative psychosomatic impact on the patient.